IP 7 Lecture 1 - Antiseizure Medications (ASM) Mechanism(s)
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24 Terms
Carbamazepine (Tegretol)
Sodium channel Blocker
Phenytoin sodium (Dilantin)
Sodium channel Blocker
Fosphenytoin sodium (Cerebyx)
Sodium channel Blocker
Clonazepam (Klonopin)
GABA Receptor Allosteric Modulator
Lorazepam (Ativan)
GABA Receptor Allosteric Modulator
Midazolam (Versed)
GABA Receptor Allosteric Modulator
Diazepam (Valium)
GABA Receptor Allosteric Modulator
Ethosuximide (Zarontin)
Voltage Gated Calcium Channel Blocker
Phenobarbital (Luminal)
GABA Receptor Allosteric Modulator + Decrease Glutamate Release
Valproic acid (Depakene, Depakote, Depacon)
Sodium Channel Blocker &
GABA-T, NMDAR, DA, 5HT
Oxcarbazepine (Trileptal)
Sodium channel Blocker
Lamotrigine (Lamictal)
Sodium channel Blocker
& Decreases Glutamate
Levetiracetam (Keppra)
Inhibit SV2A
(Inhibit Glutamate Release)
Topiramate (Topamax)
Carbonic Anhydrase 2 & 4 Inhibitor
Sodium Channel Blocker
CaV, GABA, AMPAR
Zonisamide (Zonegran)
Sodium channel Blocker & Calcium Channel Blocker
Lacosamide (Vimpat)
Sodium channel Blocker
Eslicarbazepine acetate (Aptiom)
Sodium channel Blocker
Brivaracetam (Briviact)
Inhibit SV2A
(Inhibit Glutamate Release)
Cannabidiol (Epidiolex)
TRPv, 5-HT1aR, T-Type CaV, GPR55
Cenobamate (Xcopri)
Sodium Channel Blocker & Allosteric Modulator of GABA Receptors
Felbamate (Felbatol)
Sodium Channel Blocker & Allosteric Modulator of GABA Receptors
Vigabatrin (Sabril)
Irreversible GABA-T Inhibitor
Tiagabine (Gabitril)
GABA-T Inhibitor via GAT1 Inhibition
Perampanel
Inhibit SV2A
(Inhibit Glutamate Release)