Funtional groups ✅

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41 Terms

1
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Alkane

Non reactive

Lipophilic

Van der wals

<p>Non reactive</p><p>Lipophilic</p><p>Van der wals</p>
2
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Alkene

Non reactive

Lipophilic

Van der wals

<p>Non reactive</p><p>Lipophilic</p><p>Van der wals</p>
3
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Aromatic ring

Non reactive

Lipophilic

Van der wals

<p>Non reactive</p><p>Lipophilic</p><p>Van der wals</p>
4
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Halogenated Hydrocarbon

Van der wals

<p>Van der wals</p>
5
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Aliphatic Alcohols

Hydrogen bond

Neutral under physiological conditions

Cannon ionize

<p>Hydrogen bond </p><p>Neutral under physiological conditions </p><p>Cannon ionize </p>
6
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Phenol

More acidic than alc, still neutral

Hydrogen bond

Dipole dipole

<p>More acidic than alc, still neutral </p><p>Hydrogen bond </p><p>Dipole dipole </p>
7
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Ether

Hydrogen bond acceptor

Not good water water solubility

<p>Hydrogen bond acceptor </p><p>Not good water water solubility </p>
8
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Thioether

Van der wals

<p>Van der wals</p>
9
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Aldehyde

Rare in drugs

Equilibrium w enol

<p>Rare in drugs </p><p>Equilibrium w enol </p>
10
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Ketone

Found in drugs

Equilibrium w enol

<p>Found in drugs </p><p>Equilibrium w enol </p>
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Enol

Equilibrium w aldehyde and ketone

<p>Equilibrium w aldehyde and ketone </p>
12
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Acetal-

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13
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Hemiacetal

Aldehyde in sugar

<p>Aldehyde in sugar </p>
14
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Ketal-

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15
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Hemiketal-

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16
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Amine

Most common in drugs

High water solubility

<p>Most common in drugs </p><p>High water solubility </p>
17
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Quaternary ammonium salt

Permanently charged

ion dipole (charge making it more water soluble)

not acid or base

<p>Permanently charged</p><p>ion dipole (charge making it more water soluble)</p><p>not acid or base</p>
18
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Carboxylic acid

Water soluble

Ionizable under physiological conditions

<p>Water soluble </p><p>Ionizable under physiological conditions </p>
19
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Ester

Prodrug

<p>Prodrug</p>
20
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Amide

Water soluble

Ion-dipole

<p>Water soluble</p><p>Ion-dipole</p>
21
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Carbonate

Prodrug

easily hydeolized

not stable

<p>Prodrug</p><p>easily hydeolized</p><p>not stable </p>
22
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Carbamate

Prodrug

hydrolize

not stable

<p>Prodrug</p><p>hydrolize </p><p>not stable </p>
23
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Urea

Water soluble

<p>Water soluble</p>
24
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Amidine

Strong base

Easily pronated

Water soluble

<p>Strong base</p><p>Easily pronated</p><p>Water soluble</p>
25
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Guanidine

Strong base

Easily pronated

Water soluble

<p>Strong base</p><p>Easily pronated</p><p>Water soluble </p>
26
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Sulfonic acid

Strong acid

Easily ionizable

Ion dipole

Water soluble

<p>Strong acid</p><p>Easily ionizable</p><p>Ion dipole</p><p>Water soluble </p>
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Sulfonamide

Less water soluble than sulfonic acid

<p>Less water soluble than sulfonic acid </p>
28
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Nitrate

Charged

water soluble

<p>Charged </p><p>water soluble </p>
29
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Nitrite-

Neutral

<p>Neutral</p>
30
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Oxime

Neutral

<p>Neutral </p>
31
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Hydrazone

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32
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Hydrazine-

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Hydrazide-

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34
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Oxirane

Highly strained

Highly reactive

Covalent drugs like anti cancer

<p>Highly strained</p><p>Highly reactive</p><p>Covalent drugs like anti cancer</p>
35
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Aziridine

Highly strained

Highly reactive

Covalent drugs like anti cancer

<p>Highly strained</p><p>Highly reactive</p><p>Covalent drugs like anti cancer</p>
36
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<p></p>


Pyrimidine

Cytosine

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Thymine

Pyrimidine

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Uracil

Pyrimidine

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Adenine

Purine

40
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Guanine

Purine

41
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Amino acid

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