#5: 🍄Mycology - Subcutaneous to Systemic

Chromoblastomycosis

Which disease is defined as a chronic verrucous dermatitis confined to the extremities that presents with a cauliflower-like appearance and thick-walled, copper-colored sclerotic bodies in tissue?

Eumycotic mycetoma

Which clinical condition is characterized by a triad of swelling, draining sinus tracts, and colonial granules (grains)?

Sporotrichosis

Which cutaneous and subcutaneous disease begins as a small, nonhealing ulcer on the index finger or back of the hand and progresses into a linear chain of nodular lesions along regional lymphatic channels?

Subcutaneous phaeohyphomycosis

Which subcutaneous infection presents as a localized tissue mass caused by darkly pigmented dematiaceous fungi but explicitly lacks both sclerotic bodies and draining grains?

Rhinosporidiosis

Which condition is characterized by the formation of painless polyps in the mucous membranes of the nose, eyes, larynx, and rectum?

Lobomycosis

Which superficial and subcutaneous disease presents as slowly progressing, painless, keloidal (leprosy-like)lesions that are completely unculturable on standard laboratory media?

Basidiobolomycosis

Which specialized form of entomophthoromycosis presents as a localized infection restricted entirely to the subcutaneous tissue of the arms, legs, buttocks, trunk, perineum, face, or neck?

Conidiobolomycosis

Which subcutaneous fungal infection is categorized as an entomophthoromycosis that primarily infects the tissue around the nose and on the face?

Lymphocutaneous sporotrichosis

Which clinical presentation of sporotrichosis stands as the most common presentation, typically characterized by development of nodular lesions at the point of contact that later involves the lymphatic channels and lymph nodes that drain the region?

Cutaneous sporotrichosis

Which explicit category of Sporothrix disease describes rose gardener's disease, representing the most common primary infection where the primary lesion begins as a small, nonhealing ulcer, often of the index finger or the back of the hand?

Osteoarticular sporotrichosis

Which clinical manifestation of Sporothrix schenckii is characterized by deep tracking where occurs when there is joint involvement following traumatic inoculation or systemic spread?

Pulmonary sporotrichosis

Which presentation of sporotrichosis is characterized by respiratory symptoms and occurs via inhalation of spores from the environment?

Aka verrucous dermatitis

A medical technologist is reviewing synonymous terminology used by board examiners for subcutaneous infections. What is the designated alternative name for Chromoblastomycosis?

Aka rose gardener's disease

Lymphocutaneous tracking along a linear chain of nodular lesions is a classic presentation of a dimorphic infection. What is the classic alternative name for Sporotrichosis?

Aka keloidal blastomycosis / Jorge Lobo's disease

A student notes that an unculturable subcutaneous pathogen creates slowly progressing, painless, keloidal lesions. What is the alternative name for Lobomycosis?

Fonsecaea pedrosoi, Cladophialophora carrionii, and Phialophora verrucosa

Which group represents the primary, classic causative agents explicitly documented on your sheet as the molds responsible for causing chromoblastomycosis?

Scedosporium boydii

Which agent is responsible for causing eumycotic mycetomas, which is characterized by swelling, with characteristic exudate draining to the skin surface through sinus tracts (granules)?

Scedosporium boydii

Which specific opportunistic fungal pathogen is universally documented as the primary causative agent of white-grain eumycotic mycetoma?

Phialophora verrucosa

Which dematiaceous mold features a distinct septate arrangement and is microscopically defined by vase/flask-shaped phialides with a flared, cup-like colarette where conidia accumulate at the apex?

Cladophialophora carrionii

Which mold produces long, branching chains of brown, smooth-walled, oval conidia that are delicate and accumulate at the apex of the conidiophore?

Rhinocladiella type

Which specific morphologic grouping features conidia localized directly at the tip and along the sides of the conidiophore?

Cladosporium type

Which morphologic type is explicitly characterized by conidia that are slowly branching and shield-shaped bearing chains of oval conidia?

Fonsecaea pedrosoi

Which diagnostic fungal pathogen uniquely showcases a complex mixture of four types of conidial formation under high-power evaluation?

Fonsecaea type

Which specialized morphologic type features a presentation where the end of conidiophore is swollen which bears primary single-celled, ovoid conidia (which then supports secondary conidia) and exhibits an asterisk like appearance?

Rosettelike cluster on delicate threadlike denticles

What type of conidial arrangement is produced at room temperature (RT) by the narrow, septate, branching hyphae of the Sporothrix schenckii mold phase?

Cigar-shaped cells

What structural type defines the tissue yeast phase of Sporothrix schenckii when incubated under a body temperature parameter of 37°C?

Asteroid bodies

Which specific structures represent the Splendore-Hoeppli phenomenon seen around Sporothrix schenckii in tissue but are noted as not diagnostic or not specific?

Rhinosporidium seeberi

Which unculturable pathogen forms thick-walled round tissue structures containing numerous sporangiospores or endospores?

Lacazia loboi

Which organism produces unicellular, thick-walled, lemon-shaped yeast-like cells in chains of one, two, or more cells connected by short tubules with occasional branching?

Basidiobolus ranarum

Which zygomycete produces primary conidiophores with swollen apices and globose spores that are forcibly discharged from the conidiophores?

Basidiobolus ranarum

Which organism produces secondary pyriform conidia featuring a knoblike adhesive tip that are passively discharged?

Conidiobolus spp.

Which subcutaneous zygomycete produces primary conidia that are spherical and feature prominent papilla or small bumps?

Conidiobolus spp.

Which fungal group undergoes a structural transition where a spore may develop short extensions that give rise to a corona of secondary spores?

Villose hairlike spines conidia

What distinctive morphological element appears abundantly over the surface of a Conidiobolus colony as the culture ages?

Exophiala dermatitidis

Which dematiaceous mold features pale brown conidia that accumulate at the apex of the conidiogenous cell and down the sides of the conidiophore?

Truncate apex without a collarette or conspicuous extension

What physical characteristic defines the cylindrical conidiogenous cells of Exophiala dermatitidis at their terminal tips?

Phialophora type

Which dematiaceous pathogen is described under microscopical traits as being highly similar or similar to Phialophora verrucosa?

Which specific fungal structure matches the schematic drawing showing a distinct beak-shaped or prominent zygospore formation?
Basidiobolus ranarum zygospore
Conidiobolus spp. corona conidia
Sporothrix schenckii rosettelike apex
Phialophora verrucosa flared colarette

Which opportunistic fungal pathogen features septate hyphae with simple, long or short conidiophores bearing conidia singly or in small groups?
Scedosporium boydii
Exophiala jeanselmei
Cladophialophora carrionii
Phialophora verrucosa

Which dematiaceous pathogen produces septate hyphae with numerous conidiogenous cells that are slender, tubular, sometimes branched, and characteristically tapered to a narrow, elongated tip, where conidia are oval and gather in clusters at the end and sides of the conidiophore and at points along the hyphae?
Exophiala jeanselmei
Exophiala dermatitidis
Scedosporium boydii
Fonsecaea pedrosoi

Which superficial or subcutaneous fungal genus is microscopically characterized by a pattern where the conidia form on the top and along the upper sides of the conidiophore?
Rhinocladiella spp.
Phialophora verrucosa
Cladophialophora carrionii
Exophiala spp.