Substance discovery and product development

Steps that the pharmaceutical companies develop their products before the are made available for public

Drug development

A process begin after experts/scientists identify a molecule targets (cell receptors, enzymes,…) that can be dysfunctional and cause disease and then discover new compounds that may have beneficial effects

Discovery

What is NME?

New molecular entity

The process after the NMEs is identified they will be conducted experiments → mechanism of action. potential benefits, effectiveness, dosage, route off administration,…

Development

What is FDA

In vitro

In vivo

What is IND

Investigational New Drug

The process of testing an NME through in vitro and in vivo studies → Safety and Toxicity before using in human. Researchers then analyse the results and submit IND to the FDA.

Preclinical research

The process after the FDA approves and IND submitted by a sponsor clinical trials can begin.

Clinical research