androgen receptor blockers

flutamide

major med under androgen receptor blockers

flutamide

therapeutic use

Treats prostate cancer in early stages and after metastasis

adverse effects

Gynecomastia (growth of breast tissue)

hot flashes

decreased libido

impotence

interventions

• Monitor baseline liver function monthly for first few months of treatment.

• Watch for manifestations of decreased liver function.

• Monitor for gynecomastia, reports of hot flashes, and impotence.

administration

orally - 3x daily

begin when GnRH med is started

client instructions

• Report anorexia, abdominal pain, jaundice, nausea, and dark urine to provider.

• Be aware that gynecomastia, hot flashes, and decreased sexual function can occur during treatment.

contraindications

• Allergy to the medication

• Severe liver failure with an ALT twice the expected range

• Clients who were assigned female at birth

precautions

lactase deficiency

interactions

pt taking warfarin, INR increase