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Zinc deficiency
Dermatitis ,specific skin lesions ,retarded growth, lowered feed utilization , alopecia hair loss
zin deficiency in chicks
slow growth , keratosis of the skin
selenium
toxici effect on grazing animals ( white muscle disease)
selenium deficiencies
8 mortality of newborn lams and calves, white muscle disease lambs and calves, exhudative diathesis in chicks,liver necrosis
Protein
Antibodies,carriers in blood, structural elements of the body ,hair, wool etc
proteins comprise
80% of dry, fat free body
proteins contain
C,H ,O
Proteins also contain
N
The Protein N
content is 16% for estimating the protein content of tissue and feedstuff
classifications of proteins
simple proteins, conjugated proteins,
simple proteins are
yielding only amino acids or hydrolysis
conjugated proteins
simple proteins combined with non- protein radical
nucleoproteins
one or more protein molecules with nucleic acid; high in germs of seed and in glandular tissue and liver, RNA
glycoproteins
protein molecule and a p containing subtancec, containing carbohydrate group; mucin in saliva is an example
phosphoprotein
protein molecule and a p containing substance other than a nucleic acid or lecithin eg; casein
Metalloprotein
Protein molecule and a metal; cytochrome oxidase hemoglobin
lipoprotein
protein molecule and a lipid; cell membrane
derived proteins
consist of altered and degraded products of naturally occurring proteins , produced by action of heat, enzymes, or chemical agents
protein may show up in the form of
amino acids
Amino Acids
Amino acids are the end product of protein digestion, they are the building blocks for the body protein
how many different amino acids are there
25 different amino acids present in proteins
amino acids are released by
hydrolysis by strong acids or bases by the action of certain proteolytic enzymes
neutral amino acids consist of
monamine mococarboxylic acids , monoamine dicarboxylic acids, diamond mono carboxylic acids, sulfur containing amino acids.
monoamino monocarboxylic acids
glycine, alanine, serine,valine,leucine,isoleucine,threonine
monoamino diacarboxylic acid
asparatic acid , glutamic acid
diamino mono carboxylic acid
Arginine , lysine, citrulline
Sulfur containing amino acids
cystine, cysteine, methionine
Aromatic amino acids
phenylalanine , tyrosine
Heterocyclic amino acids
Histidine, proline, hydroxyproline,tryptophan
Amino acids and proteins are
amphoteric, behave as acids and as bases since they contain at least one carboxyl group and one amino group
10 amino acids as dietary essentials
must be contained in the diet consumed ( methionine, arginine,threionin, tryptophan, histidine, isoleucine, leucine, lysine, valine, phenylalanine)
In poultry
Glycine and Serine are needed
two aspects of protein nutrition quality are
quantitive phase, qualitative phase
quanatative phase
the gross number of amino acids present in the feedstuffs
qualities phase
the proper balance of essential amino acids to meet the animals needs, the balance of essential amino acids is refer to as protein quality
protein digestion in non ruminants
recreation,gastric juice, pancreatic juice,intestinal juice
gastric juice
pepsinogen I II — Pepsin ,parapepsin I , Perapepsin II
Minerals
structural component of teeth bones, cofactors for enyzmes, constituents of essential components in body, constituents of body fluids like blood.
mineral deficiencies
sub optimal amount in feed , imbalance of another mineral ,any condition which increases rate of passage , A metabolic antagonist which causes animal to require more dietary mineral
Mineral excretion routes
Some almost entirely in feces, some in urine, some both routes, some lost in sweat, F ay be lost due to blood loss
Many minerals are involved in a process called
Chelaton
Chelation
A chelating agent, or chelator, will bind a mineral to varying degrees. Isolating minerals from interactions with compounds
Nutritionally
May bind trace elements in diet and then release them at site where needed, prevents other interactions during digestion
Medical Functions
Remove certain isotopes or poison from the body 6 binds them, then the complex is excreted
natural chelators
hemoglobin
Calcium
One of the most important minerals of the body
Adequate calcium and phosphorus depends on 3 factors
sufficient supply of Ca & p, suitable ratio between the TWO 1:1-2:1, the presence of vitamin D
Distribution
99% Ca and 80% P in bones and teeth + major structural component
Bone formation occurs in
Occurs In soft tissue such as blood serum, muscle, tissues. represents 1% of calcium
Calcium Absorption
Regardless of the form ingested , absorption depends on its solubility at the point of contact with absorbing membranes, absorption occurs primarily in proximal portions gut, factors conducive to Ca absorption
calcium exit route is
feces route
Calcium Deficiency
reduced growth, especially bone, hyper irritability and tetany, poor reproductive perfoemcne , rickets,ostemaalacia
calcium rickets
growing bones that tend to bend under wight of animal
osteomalacia
Occurs in adult bone, involves a softening of the bone due to a decrease in mineral content . Slow drain over time may lead to weakness, deformity,spontaneous fractures
calcium defecniency in swine and poultry
Are most likely to be deficient in calcium due to their very rapid growth rate and their diets, grains and proteins concentrates are lower in calcium than roughages
Phosphorus
physiologically and biochemically it is one of the most important minerals
phosphorus distribution
80% of p is in bone, whole blood 35-45mg,inorganic p in plasma 4-9mk
Phosphorus functions
Bone formation 80% phosphorus in bone, remaining 20% involves ed in most organic reactions as an enzyme
phosphorus functions
necessary for phosphorylations in CHO metabolism, energy transfers - NAD, constituents of ATP, constituents nucleoproteins , phosphoproteins, DNA, RNA,
phosphorus deficiencies
Decreased growth, decreased bone growth, rickets or osteomalacia ,pica
Phosphorus deficiency PICA
Pica occurs in grain animals 6 fragile bones, lameness, low fertility, also known as depraved appetite;
In young confined calves
Problems are usually dye to lack of vitamin D
magnesium distribution
About 70% of the body supply is in skeleton, remainder or 30% is distributed in body fluids and tissue, blood normally 2-3mg, about 1/3 of skeletal Mg.
Magnesium Functions
Bone formation, enzyme activator (ex. Pyryvate), Helps decrease nerve irritability
magnesium absorption site
Small intestine for all animals and also the rumen of ruminants, mechanisms +active transport of stubble Mg salts.
Magnesium deficiencies
Low blood Mg , vasodilation, hyper irritability convulsions and death. Grass tetany
Low magnesium levels =
Nervousness, loss of appetite, trembling, convulsions, coma, death
Sulfur is bound organically
Body contains 0.15% sulfur, containing amino acids, cystine and methionine
sulfur is
Most present in amino acids, small amount is present in inorganic sulfate, another portion is present in various organic compounds; insulin and glutathione
sodium mineral
has 0.2% Na mostly in body fluids
sodium occurrence makes up
93% of bases in blood serum
sodium absorption
rapidly absorbed from small intestines, small amount from stomach
sodium functions
ostmotic pressure regulation- helps maintain norm H2O
Sodium deficiencies include
Decreased feed consumption, poor growth and production , emaciation or wasting away
potassium
contains 0.2%, occurs primarily in intracellular fluid, absorption- small intestine.
potassium functions
osmotic pressure, acid base balance, muscle contraction, nerve impulses, enzyme cofactor
potassium deficiency is
reduced growth, heart lesions, tubular degeneration of kidneys , K deficiency during pregnancy
chlorine
inside and outside cells
chlorine functions
Osmotic pressure, acid base balance, gastric recreation in stomach as free HCI and as salts
chlorine absorption
Small intestine, excretion is in kidney
Iron
70% of iron is found in form of hemoglobins thus most iron is bound organically in body
iron absorption
Absorbed only when body is deficient in mineral
iron factors influencing absorption
Acid condtion, adequate dietary protein, body need for iron, low physic acid level in diet , histidine and lysine
functions of iron
Cytochrome, peroxidase,catalase b
iron deficiency
Anemia
Iron anemia
Pathological , hemorrhagic, hereditary, nutritional
copper functions
Hemogoblin synthesis , important as a catalyst .
copper functions
activates certain enzymes such as ascorbic acid oxidase
copper deficiencies
wastin diss, enzootic ataxia, falling disease of cattle, nutritional anemia, grain of black hair and wool
wasting disease
characterized diarrheas loss of appetite and anemia
enzootic ataxia
this occurs in newborns lams and is associated with low copper content of the dam during pregnancy.
falling disease of cattle
very similar to enzootic ataxia of sheep and is characterized by falling and sudden death
nutritional anemia
characterized by microcytic , hypo chromic has been observed on Cu.
graying of black hair and wool
failure of melanin formation ( no tyrosinase )
Cobalt functions
Constituent of the vitamin B -12 molecule, can also serve as enzyme co favor
cobalt deficiency symptoms
listless, weak, loss of appetite and weight, Anemic
cobalt bullet
Extremely hard pellet of a cobalt compound , last several months
iodine
a constituent thyroxine hormone
hypothyroid condition
low thryxoic recreation low metabolic rate
hyperthyroid
high thyroxin, high metabolic rate, hyper practical