insulin types - exam 3

rapid acting insulins

lispro (humalog)

aspart (novolog)

glulisine (aspidra)

rapid: onset/ peak/ duration

15-30 min / 1-3 hr / 4-6 hr

Rapid: when to give, and key risk?

Just before a meal. Highest risk of hypoglycemia.

Short-acting insulins?

Regular (Humulin R, Novolin R)

Short: onset / peak / duration?

30-60 min / 2-4 hr / 5-8 hr

Short: when to give, and special use?

30-60 min before a meal. Useful for managing DKA.(type1)

Intermediate-acting insulins?

NPH (Humulin N, Novolin N)

Intermediate: onset / peak / duration?

2-4 hr / 8-12 hr / 10-18 hr

Intermediate: role?

Basal insulin that covers insulin need for about half a day.

Long-acting insulins?

Glargine (Lantus), Detemir (Levemir)

Long: onset / peak / duration?

1-2 hr / no peak / 24+ hr

Long: role?

Basal insulin that covers insulin need for about 1 day.

Ultra-long-acting insulin?

Degludec (Tresiba)

Ultra-long: onset / peak / duration?

1 hr / no peak / 42+ hr

Ultra-long: use?

Extra-long glucose control.

Which insulins have no peak?

Long (Glargine, Detemir) and Ultra-long (Degludec)