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UNIT 2 formation of facial cavities
Done
What happens as a result of maxillary prominencens medial growth
Medial nasal prominences merge at surface + deep
What does the merging of 2 medial nasal prominences form
Intermaxillary segment

What is the intermaxillary segment comprised of
Labial component
Maxillary component
Palatal component
What does the labial component form Of intermaxilalry segfment
superior lip philtrum
What does the maxilary compoent of the intermaxillary segment carry
4 incisors
What does the palatal comoennt of the intermaxillary segment form
Triangular primary palate
What is the intermaxillary segment continuous with
Ventral nasal septum
What divides the priary and secondary palate
Incisal foramen

When does development of paalte begine
Week 5
When does palate fusion finish
Weekm 12
What is the palate formed by
Primary palate
Secindary palate
What is the primary palate aka
Intermaxillary segment
what is the secondary paalte formed by
2 palatine shelves / lateral palatine processes

where do the palatine shelves initially frow
Downward alongside tongue
Where do the palatine shelves move to
Elevate to horizontal position above tongue
(When they form the secondary palate)
What happens if the elevation +fusion of the palatine shelves fails
Cleft palate
What is the triangular primary palate aka
Incsive foramne
What do the palatine shelves fuse with anteriorly
Incisivce foramen
What is the midline betwen the primary adn secondary palate
Incisive foramen
What happens to the nasal septum as the palatine shelves fuse
Nasal septum grows caudally and joins the newly formed palate
Nasal and oral cavity development
Done
Where do the nasal and maxillary prominences fuse
On the surface and depth of stomodeum
What membrane is torn at the end of the 3rd week
Buccopharyngeal membrane
what does tearin g of the buccopharyngeral membrane connect
Ectodermal oral cavity with endodermal foregut
What does the growth of the nasal prominences split
Nasal cavity from oral cavity
what does the growth of nasal prominences and their penetration inot the underlying mesenchyme cause
Nasal pit to deepen
What membrane pslits the nasal pits from the oral cavity
Oronasal / bucconasal membrane
What is openly connected after the oronasal membrane breaks down
Nasal and oral cavities
What new foramina is formed to connect the oral and nasal cavities
Primitive choanae
After the secondary palate formation, where do the internal nostrils shift Into
Into nasopharynx
Via ? Do the the internal nostrils shift
Definitive choanae
After the definitve choanae are formed and in place what is formed
Definitive nasal cavity
Where does the nasal septum ascend from
Medial nasal prominence with the palate
What do the lateral walls of the nasal cavity develop
Superior, middle and inferior conchae
What does the ectodermal epithelium in the roof of nasal cavity become
Specialised olfactory epithelium
What gives rise to the olfactory nerve fibers
Olfactory cells in olfactory epithelium
What do the olfactory nerve fibers grow into
Olfactory bulbs
When dothe paranasal sinuses form
Postnatally
What do the paranasal sinuses form as
Sacs of the nasal cavity
What is the final form of the nasal and oral cavities
(3 things)
Primary and secondary palates
Choanae at their junction
Pharynx

Look
Dome
What divides the anterior and posterior clefts
Incisive foramen
What is anterior to the incisive foramen
(3 things)
Lateral cleft lip
Cleft maxilla
Cleft between 1 and 2 palate
What are the anterior clefts formed by
Lack of fusion of amxillary prominence with medial nasal prominence
What are tge clefts posterior to the incisive froamen
2 thinfs
Cleft secondary palate
Cleft uvula
What does a cleft palate a result of
Lack of palatine shelves fusion
What can cause lack of palatien shelf fusion
shelf too small
Shelf does not elevate
Micrognathia
What is micrognathia
Lower jaw is underdeveloped —> receding chin
What is produced from a failure of maxillary prominence to merge with corresponding lateral nasal prominence
oblique facial cleft
What does a onlique facial cleft cause
Nasolacrimal duct to be exposed
What is produced from a failure Of merging of 2 medial nasal prominence in middle line
Median cleft lip
Which has lower frequency
Isolated cleft palate
Cleft lip
Cleft palate
What can cause clefts
Exposure to teratogenic compounds e.g anticonvulsant medication
Where does failsure of fusion of maxillary prominence and medial nasal prominence affect up to (3 things)
Lip
Alveolar bone
Primary palate
What causes cleft of secondary palate
Incomplete fusion of 2 palatine shelves
What does failure of fusion between maxillary prominence wth medial nasal prominence cause
Cleft lip