Unit 19 - Oxidative Phosphorylation

Exam 3

glycolysis occurs in the…

the citric acid cycle occurs in the…

oxidative phosphorylation occurs in the…

cytoplasm, mitochondrial matrix, inner membrane of the mitochondria

describe this reaction

highly thermodynamically unfavorable

how do we phosphorylate ADP?

energy needed to phosphorylate ADP is provided by the flow of protons down the electrochemical gradient

the proton gradient is formed using the energy released by _______ _______

electron transport

the proton gradient is when protons are moved ________ the electrochemical gradient using energy released by electron transport

against

what converts the energy of the proton gradient into ATP?

ATP synthase

point out where each process occurs:

glycolysis

citric acid cycle

oxidative phosphorylation

in the electron transport chain, electrons flow _____ an energy gradient from ______ to ___

down, NADH, O2

the flow down the electron transport chain is catalyzed by _____ protein complexes

four

what are the three protein complexes that catalyze the electron transport chain?

1. complex I → NADH-Q oxidoreductase

2. complex III → Q-cytochrome c oxidoreductase

3. complex IV → cytochrome c oxidase

what is complex I called?

NADH-Q oxidoreductase

what is complex II called?

succinate Q reductase

what is complex III called?

Q cytochrome c oxidoreductase

what is complex IV called?

cytochrome c oxidase

NADH goes into complex __ while FADH2 goes into complex __

I, II

complexes I, III and IV are considered ____ _____

proton pumps

is complex II (succinate-Q reductase) a proton pump?

no

complexes I, III and IV pump protons out of the _____________ ______, generating a proton gradient

mitochondrial matrix

where is the electron transport chain found?

the inner membrane of the mitochondria

the electron transport chain pumps protons into…

intermembrane space

what is the role of succinate Q-reductase (complex II)?

succinate Q-reductase delivers electrons from FADH2 to complex III

what is the final enzyme acceptor in the electron transport chain?

O2

outline the flow of electrons in the electron transport chain from NADH to O2

…