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muscles are responsible for
body movement
what structures create the contractions exhibited by muscles?
myofilaments: contractile proteins
cardiac muscle control
involuntary
smooth muscle control
involuntary
skeletal muscle control
voluntary
number of nuclei in cardiac muscle
uninucleate
number of nuclei in skeletal muscle
multinucleate
number of nuclei in smooth muscle
uninucleate
cardiac muscle cell shape
branching cell
skeletal muscle cell shape
large, cigar-shaped
smooth muscle cell shape
spindle-shaped
cardiac muscle striations
striated
skeletal muscle striations
striated
smooth muscle striations
nonstriated
cardiac muscle location
heart walls
skeletal muscle location
attached to bones via tendons
smooth muscle location
hollow tubes
4 major functions of skeletal muscles
produce movement
maintain posture and body position
stabilize joints
generate heat
4 types of connective tissues found in skeletal muscles
endomysium: encloses a single muscle fiber
perimysium: wraps around a fascicle (bundle) of muscle fibers
epimysium: covers entire skeletal muscle
fascia: on the outside of epimysium for large areas of body
endomysium
inner-most layer of connective tissue found in skeletal muscle
encloses a single muscle fiber
perimysium
connective tissue found in skeletal muscle
wraps around a fascicle (bundle) of muscle fibers
epimysium
outer layer of connective tissue found in skeletal muscle
covers entire skeletal muscle
fascia
outer-most layer of connective tissue found in skeletal muscles
wraps epimysium for extra support to large areas
2 structures that can form from the epimysium
tendons: stiff cord-like structures composed of collagen fibers
aponeuroses: sheet-like structures that attach muscles indirectly to bones, cartilages, and connective tissue coverings
tendons
attach skeletal muscles to bones and form from the epimysium
cord-like structures that are very stiff
composed of collagen fibers
located on a joint because of their toughness and small size
aponeuroses
attach muscles indirectly to bones, cartilages, and connective tissue coverings
sheet-like structures that form from the epimysium
origin
a muscle’s starting point
insertion
a muscle’s ending point → part doing the movement
how does a muscle move?
moves the insertion (end) towards the origin (beginning)
shape of a muscle fiber
long, cylindrical, and has multiple nuclei
sarcolemma
muscle fiber plasma membrane
sarcoplasm
muscle fiber cytoplasm
glycosome
glycogen (glucose) storage
myoglobin
for oxygen storage and transport
sarcoplasmic reticulum
specialized smooth endoplasmic reticulum
surrounds myofibril
stores and releases calcium ions
t tubules
extension of sarcolemma
allows for faster nerve impulse transmission deeper into the muscle fiber
stimulates sarcoplasmic reticulum to release calcium ions
myofibrils
densely packed, rodlike elements that are striated
a single muscle fiber contains thousands
account for around 80% of cell volume
sarcomeres are packed into myofibrils
i band
in myofibril → light band
contains only thin filaments called actin (acthin)
z disc interrupts this band midway
a band
in myofibril → dark band
contains only thick filaments called myosin
h zone is the lighter central region within the a band
m line is the center of the h zone
anchor point for myosin
sarcomere
contractile unit of a muscle fiber → all contractions result from the shortening of sarcomeres
sarcomere shortened when z discs are pulled to m line
consists of myosin and actin
myofilaments
type of contractile protein found in sarcomeres
thick filaments = myosin
thin filaments = actin
thick filaments
composed of myosin
contain proteins called ATPase: enzyme that breaks down ATP to release energy for contractions
contain myosin heads that allow myosin to bind to actin filaments
allows for formation of cross bridges
ATPase
found in thick filaments → enzyme that breaks down ATP to release energy for contractions
myosin heads
found in thick filaments → allow myosin to bind to actin filaments
cross bridges
links that form when myosin heads attach to actin filaments
thin filaments
composed of actin → anchored at z disc
at rest, h zone within a band lacks actin
during contraction, h zone disappears as actin and myosin filaments overlap
tropomyosin and troponin: regulatory proteins bound to actin
tropomyosin and troponin
regulatory proteins bound to actin
satellite cells
type of stem cell found in muscle fibers or outside sarcolemma
aid muscle repair and growth via protein synthesis and nucleus donation
repair capacity is limited
3 reasons why connective tissue wrappings of skeletal muscle are important
provide extra support
durability and protection
keep blood vessels in place
characteristics of skeletal muscle
irritability: ability to receive and respond to a stimulus
contractibility: ability to forcibly shorten when adequate stimulus is received
extensibility: can be stretched
elasticity: can recoil to original or resting length after stretching
irritability
ability to receive and respond to a stimulus
contractibility
ability to forcibly shorten when adequate stimulus is received
extensibility
can be stretched
elasticity
can recoil to original or resting length after stretching
cell that stimulates a muscle to contract
motor neurons activate muscle fiber
action potentials
electrical signal at the membrane
excitable cells (neurons and muscle cells) can change the resting membrane potential voltages
neurotransmitter that stimulates muscle fibers
acetylcholine → transmits signal from neuron to muscle cell
role of ion channels
changing membrane potentials → required for muscle contractions to occur
chemically-gated ion channels
opened by neurotransmitters
ex. acetylcholine receptors on muscle cells
voltage-gated ion channels
open or close in response to voltage changes in membrane potential
axon of motor neurons
long, threadlike extension of motor neurons that carry signals from the cell body to the axon terminal
central nervous system to skeletal muscle
axon divides into many branches as it enters the muscle
axon terminal
end of axon
contains synaptic vesicles that contain acetylcholine
synaptic vesicles
intracellular containers located in the axon terminal that contain acetylcholine
moves transmitters around the cell
synaptic cleft
gel-filled gap between the neuron and the next cell
junctional folds
infolding of sarcolemma
increase surface area of sarcolemma
contain millions of acetylcholine receptors
3 components of neuromuscular junction
axon terminal
synaptic cleft
junctional folds
neuromuscular junction
where axon terminal meets sarcolemma
motor unit
one motor neuron and all the skeletal muscle cells stimulated by that neuron
more units are used each time for bigger things
each cell talks to one neuron but one neuron can talk to a group of cells