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blood calcium regulation hormones
PTH and calcitriol
PTH
released by parathyroid glands when blood Ca2+ is low
3 targets
increased absorption of ca2t from small intestine into blood.
Osteoclasts activation releasing Ca2+ from bone
Increased reabsorption Ca2+ from kidney.
Calcitonin
Released when Ca2+ is high and response to stress
What does calcitonin inhibit and increase?
Inhibits osteoclasts, increase osteoblasts
What does calcitonin stimulate
Stimulates kidney to increase Ca2+ excretion
Calcitriol
Active form of vitamin D, increases calcium absorption.
PTH & Calcitriol interact with bone
increase release of CA 2+ from bone by increasing osteoclast activity.
PTH & Calcitriol interact with kidney
stimulate kidney to excrete less Ca 2+ in the urine.