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IBS Patho
does not have a specific pathophysiology since a diagnosis is typically made when other, more definitively diagnosed intestinal conditions have been ruled out
Dysfunction in gut-brain connection or hypersensitivity of GI nerves
IBS-C (constipation presentation)
IBS-D (diarrhea presentation)
IBS-M (mixed presentation)
IBS Risk Factors
Female
Young
Family Hx
Emotional distress
Food sensitivities
Meds
antidepressants, ABX, meds manufactured w/sorbitol
IBS Sx
Violent or uncontrollable changes in bowel habits…diarrhea or constipation
Abd. pain or cramping
Abd. bloating
Flatulence
Blood or mucous stool in stool without indication of disease
must occur weekly for three months or less often for at least six months.
IBS Labs
Diagnosed by ruling out other conditions
ROME criteria
IBS Tx
Lifestyle modifications
reducing stress
avoid trigger foods
adequate exercise and sleep
monitor fluid intake (dehydration prevention)
Meds
Lower GI Tract
• Jejunum • Ileum
• Caecum • Ascending colon
• Descending colon • Sigmoid
• Rectum • Anus
Crohn’s Disease Patho
inflammation of the deeper layers of structures lining the GI organs that lie anywhere between the mouth to the anus.
Patches of inflammation followed by patches of healthy tissue.
transmural inflammation
Ulcerative Colitis Patho
affects the colon and rectum.
Continuous pattern of small sores or ulcers of the superficial mucosa and submucosa that lines these specific areas of the large intestine.
Crohn’s Disease Risk Factors
Cigarette smoking (or second-hand exposure)
Fetal or childhood exposure to ABX
Appendectomy or tonsillectomy early in life
20-30 years of age
Ulcerative Colitis Risk Factors
Past viral or bacterial infections
60-79 years of age
Smoking REDUCES risk
Crohn’s Disease Sx
Diarrhea
Rectal bleeding
Abd.pain
Decreased appetite
Abscess formation
Fistulas around anus
Skin lesions or joint pain
Ulcerative Colitis Sx
Stool urgency
Fatigue
Increased bowel movement
Mucous in stool
NOCTURNAL bowel movements
Abd. pain
IBD Labs
EGD
flexible sigmoidoscopy
Endoscopy
Colonoscopy
X-ray, CT, or MRI
IBD Tx
Anti-inflammatories, immunosuppressants, or biologic medications
ABX to address complications
Vitamin and mineral supplements
Smoking cessation
Stress reduction therapy…mediation etc
Diverticulosis
Outward facing sacs along the intestinal tract that form because of areas of weakness.
Diverticulitis
diverticula can become inflamed or develop infections
Celiac Disease
Autoimmune disease causing extreme gluten sensitivity
Over time, the inner lining of the small intestine can be damaged, and malabsorption can occur due to ingestion of this protein.
Bowel Obstruction
occurs when there is either a structural or functional issue that causes a blockage in the small or large intestine that keeps food or liquid from passing through.
Bowel Obstruction Risk Factors
Intra-abdominal adhesions
prior abdominal or pelvic surgery
IBD
Cancer
Diverticulitis Risk Factors
increased age
obesity
smoking
lack of exercise
Low fiber diet
Certain medications such as steroids, opioids, and NSAIDs.
Celiac Disease Risk Factors
Family Hx
T1DM
Down Syndrome
Turner Syndrome
Autoimmune thyroid issue
Microscopic colitis
Addison’s disease
Bowel Obstruction Sx
Sharp or cramping pain
Bloating
Distention of abdomen
Diarrhea or inability to pass stool or gas
Loss of appetite
N/V
Diverticulitis Sx
Persistent abdominal pain
N/V
Elevated temp
Abd. tenderness
Constipation or diarrhea
Complications may include abscess formation, bowel blockage, fistula development, or peritonitis.
Celiac Disease Sx
Diarrhea
Fatigue
Weight loss
Bloating
Increased flatulence
Anemia
Complications loss of bone density, mouth ulcers, neuropathy, joint pain, or reduced function of the spleen.
Celiac Disease Labs
blood test called tissue transglutaminase IgA antibody (tTG-IgA) i
Colostomy Education
Nurses should teach that the pouch should be emptied when one-third full to prevent leaks.
The appliance should be changed every 5 to 7 days or sooner if leakage or skin irritation occurs.
Clients should monitor the peristomal skin for redness, irritation, or breakdown and use protective barriers as needed.
Proper hand hygiene and safe disposal of soiled materials must also be emphasized.
Bowel Obstruction Tx
Partial bowel obstructions may be treated with laxatives to promote GI motility and dietary changes to reduce the bulk of food traveling through the intestines.
Complete bowel obstructions need to be treated urgently. Most client will be hospitalized to receive IV fluid replacement, nasogastric tube placement to remove excess fluids, medications to decrease nausea and pain, and potential surgery to remove adhesions or scar tissue that may be causing the obstruction.
Diverticulitis Tx
increasing dietary fiber intake
antibiotics if infection occurs
possible surgical intervention such as a colon resection or colectomy, for complications related to intestinal obstruction or perforation.
Celiac Disease Tx
Strict anti-gluten diet
Ileostomy if sx are severe