session 31 practice

For a pharmaceutical solution, a drug could be completely dissolved or partially dissolved in the solution.

 

True

 

False

False

When prepare a solution, pharmacists need to pay attention to:

 

Solubility of the drug in the solution

 

Stability of the drug in the solution

 

Possible interactions of the drug with solutes/excipients

 

All of above

 

Properties of solvents

All of above

Solubility is temperature dependent.

 

True

 

False

True

Which of the following contains 70% alcohol?

 

Dehydrated alcohol

 

Alcohol, USP

 

Diluted alcohol

 

Rubbing alcohol

Rubbing alcohol

Syrups are aqueous solutions that could be with or without drugs.

 

True

 

False

True

What is the risk of applying heat in drug solution preparation?

 

Heat reduces viscosities of solvents

 

Heat increases drug dissolution

 

Drug that dissolves at high temperature could precipitate out after cooled down.

 

Heat changes drug taste

Drug that dissolves at high temperature could precipitate out after cooled down

Freezing diluted syrups at -80C is an effective approach to prevent microbial growth.

 

True

 

False

False

Which of the following is not a hydroalcoholic oral solution?

 

Spirits

 

Elixirs

 

Tinctures

 

Syrups

Syrups

What is a common method used to increase the dissolution rate of drugs in solutions?

 

 

Increasing the particle size of the solute

 

Decreasing the temperature

 

Vigorous mixing or stirring

 

Using fewer solvents

Vigorous mixing or stirring

Which of the following is an advantage of solutions as a dosage form?

  

 

Drug is immediately available for absorption

 

Solutions are less bulky and easier to transport

 

Drug stability is improved in solution form

 

Solutions are easy to mask unpleasant tastes

Drug is immediately available for absorption

What is the primary characteristic of a pharmaceutical solution?

 

 

 

A solid preparation of a drug mixed with excipients

 

A liquid preparation with one or more chemical substances dissolved in a solvent

 

A powder formulation for oral administration

 

A suspension of drug particles in a solvent

A liquid preparation with one or more chemical substances dissolved in a solvent

Which of the following is a disadvantage of solutions as dosage forms?

  

 

Drugs are immediately available for absorption

 

Solutions are bulky and difficult to transport

 

Solutions can mask unpleasant tastes effectively

 

Solutions do not require measuring devices

Solutions are bulky and difficult to transport

Which solvent is commonly used in pharmaceutical oral water-based preparations and also acts as a preservative?

 

 

Corn oil

 

Tap water

 

Ethyl alcohol

 

Sesame oil

Ethyl alcohol

Which of the following is true about purified water USP?

  

 

It is used for parenteral administration.

 

It is acceptable for most injectable formulations.

 

It is acceptable for manufacturing injections.

 

It is obtained through processes like distillation or reverse osmosis

It is obtained through processes like distillation or reverse osmosis

Which of the following is NOT true about tinctures?

 

 

They are often used for extracts from plant or chemical sources.

 

They are self-preserved due to the high alcohol content.

 

They are typically prepared without alcohol.

 

They contain 15-80% alcohol

They are typically prepared without alcohol