DNA Damage and Repair- Genetics Exam 2

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Last updated 11:23 PM on 10/19/26
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7 Terms

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Ionizing Radiation

Breaks DNA double strands (X-rays)

2
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UV Radiation

Forms thymine dimers (UV light (sunlight))

3
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Deaminating Agents

Remove amino groups from bases, changing base pairings (Nitrous Acid (HNO2))

4
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Intercalating Agent

Inster between DNA bases, causing frameshifts and DNA helix distortion (Ethidium Bromide, & Proflavine)

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Base Analogs

Mimic normal bases and are incorporated during replication (5-Bromouracil (5-BU))

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Hydroxylating/ Oxidizing Agents

Create oxidized bases that mispair (Hydroxyl Radicals (-OH, ROS))

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Alkylating Agents

Add methyl, or ethyl groups to bases, altering pairing (EMS, MMS, Nitrogen Mustards)