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4 (or 5) somatic sensory modalities
Touch, pressure, proprioception, pain, temperature
Quantitative sensations
Touch, pressure (vibration), proprioception
Qualitative sensations
Pain, temperature
Is balance a somatic sensory modality?
No (special sense)
Ascending spinal tracts are
Sensory afferents
Dorsal root carries
Sensory (afferent) axons
Dorsal root ganglion contains
Cell bodies of 1st-order sensory neurons
Ventral root carries
Motor (efferent) axons
Spinal nerve carries
Both sensory and motor fibres
Dermatome
Area of skin supplied by one spinal level
Spinal epidural space is filled with
Adipose tissue and blood vessels
Pathways using a 3-neuron system
Sensory pathways (e.g. spinothalamic, DCML)
1st-order sensory neuron
Receptor → DRG → spinal cord
2nd-order sensory neuron
Ascending tract (decussates) → thalamus
3rd-order sensory neuron
Thalamus → internal capsule → postcentral gyrus
Extra structure where sensory (but not motor) pathways synapse
Thalamus
Internal capsule
Projection fibres between thalamus and basal nuclei; sensory + motor; becomes corona radiata
Does the 3rd-order neuron decussate at the thalamus?
No
Spinothalamic tract carries
Pain and temperature
Spinothalamic receptors
Free nerve endings
Spinothalamic 1st synapse
Dorsal horn grey matter of the spinal cord
Spinothalamic decussation
Spinal cord
Spinothalamic ascends on which side?
Contralateral (opposite the stimulus)
Spinothalamic 2nd synapse
Thalamus
Spinothalamic extra terminations
Temporal lobe (memory/emotion), reticular formation (pain modulation, alertness)
Spinothalamic fibres cut before decussating → deficit side
Ipsilateral
DCML stands for
Dorsal column - medial lemniscus
DCML carries
Touch, pressure, vibration, proprioception
DCML ascends in the spinal cord on which side?
Ipsilateral (same side)
Gracile fasciculus carries
Info from the legs (below T6); sensory, not motor
Cuneate fasciculus carries
Info from the arms (above T6)
Spinal level separating gracile and cuneate input
T6
Left cuneate fasciculus carries
Proprioception (and touch) from the left upper limb
DCML 1st synapse
Medulla (nucleus gracilis / nucleus cuneatus)
Leg fibres in DCML synapse in
Nucleus gracilis
DCML decussation
Medulla
After decussating, DCML fibres become the
Medial lemniscus
DCML 2nd synapse
Thalamus
Spinal pathway for touch
DCML
Proprioception to the cerebellum travels via
Spinocerebellar tract (ipsilateral, inferior cerebellar peduncle)
Spinocerebellar receptors
Muscle spindles and tendon organs
Left dorsal column lesion →
Loss of touch/pressure/vibration on the LEFT below the lesion
Right spinal cord hemisection at T8 →
Right loss of proprioception/touch; left loss of pain/temp, below T8
Left spinal cord hemisection at T12 →
Left leg loses touch/pressure/proprioception; right leg loses pain/temperature
Left pain/temp loss + right touch loss → lesion site
Right spinal cord
Right medial lemniscus (medulla) lesion →
Left touch and proprioception lost
Can't feel vibration in toes but pain intact → tract
DCML
Lesion above the medulla → sensory loss side
Opposite (contralateral) for everything
Interoceptors
Autonomic sensory receptors inside organs
Visceral vs somatic pain quality
Visceral = dull, poorly localized; somatic = sharp, well localized
Mechanism of referred pain
Visceral and somatic fibres converge on the same 2nd-order neurons in the dorsal horn; brain can't tell the source
Gallbladder pain felt in the right shoulder is
Referred pain
Why appendicitis pain moves to the RLQ
Somatic fibres in the abdominal wall become involved
Dermatome levels by plexus
Brachial C5-T1; intercostals T1-T12; lumbar L2-L5; sacral S1-S4
Dorsal vs ventral rami
Branches of the spinal nerve to the back vs. front of the body
Spinothalamic collaterals go to
Medullary and pontine reticular formation and periaqueductal grey (pain modulation, alertness)
Spinocerebellar tract enters the cerebellum via
Inferior cerebellar peduncle
Do autonomic sensory fibres travel with motor fibres?
Yes - they follow autonomic motor fibres to the spinal cord, then join the spinothalamic pathway