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thyroid gland
calcitonin
pineal gland
melatonin
polyuria
excessive urine production
parathyroid gland
stimulated by low blood calcium level
thymus gland
atrophies by adulthood
adrenal cortex
secretes androgens, mineralocorticoids, and glucocorticoids
heart
atrial natriuretic peptide
endocrine pancreas
islets of Langerhans
gonadotropins
FSH and LH
hypothalamus
secretes regulatory hormones
pituitary gland
hypophysis
growth hormone
stimulates cell growth and protein synthesis
What is the primary function of the endocrine system?
Secretes hormones that regulate body functions and maintain homeostasis.
How does endocrine communication differ from nervous communication?
Hormones travel through blood; nervous signals are generally faster and more targeted.
Which gland secretes melatonin?
Pineal gland; regulates circadian rhythms and sleep–wake cycles.
What are the six major anterior pituitary hormones?
GH, TSH, ACTH, FSH, LH, and prolactin.
Which two hormones are released by the posterior pituitary?
ADH and oxytocin; both are synthesized by the hypothalamus.
What does growth hormone (GH) do?
Promotes body growth and protein synthesis.
What does ACTH stimulate?
The adrenal cortex, especially cortisol secretion.
What do FSH and LH regulate?
Reproductive functions: FSH supports follicles and sperm production; LH triggers ovulation and stimulates testosterone production.
Which thyroid hormone helps lower blood calcium?
Calcitonin; it can inhibit bone resorption.
What does parathyroid hormone (PTH) do?
Raises blood calcium; secretion increases when blood calcium is low.
Which element is required to synthesize thyroid hormones?
Iodine; required for T3 and T4 production.
What are the adrenal cortex's three major hormone categories?
Mineralocorticoids, glucocorticoids, and androgens.
Which hormones are secreted by the adrenal medulla?
Epinephrine and norepinephrine; support fight-or-flight responses.
What does aldosterone do?
Increases kidney sodium reabsorption and potassium secretion.
What does ADH do, and what happens if it is deficient?
ADH conserves water; deficiency can cause diabetes insipidus and excessive dilute urine.
What do pancreatic insulin and glucagon do?
Insulin lowers blood glucose; glucagon raises blood glucose.
What is polyuria? What is polydipsia?
Polyuria = excessive urination; polydipsia = excessive thirst.
What causes the symptoms of diabetes mellitus?
Insulin deficiency or resistance causes hyperglycemia; urinary glucose can draw water out, causing polyuria and thirst.
What are the three phases of general adaptation syndrome?
Alarm, resistance, and exhaustion.
What happens when phosphodiesterase is inhibited in a cAMP pathway?
cAMP breakdown slows, potentially prolonging the hormone's intracellular signaling.
What does the QRS complex represent on an ECG?
Ventricular depolarization
Which hormone helps lower blood volume and blood pressure by increasing sodium and water loss?
ANP (Atrial Natriuretic Peptide)
Which cells are mainly responsible for cell-mediated immunity?
T Lymphocytes
Helper T cells recognize antigens presented with which MHC protein?
Class II MHC
What is the main function of the hepatic portal system?
Transporting nutrient-rich blood from digestive organs to the liver
Which structure normally acts as the heart's pacemaker?
SA node (Sinoatrial node)
Which valve is located between the right atrium and right ventricle?
Tricuspid valve
Which heart chamber pumps oxygenated blood into the systemic circulation?
Left Ventricle
Which blood vessels carry deoxygenated blood from the heart to the lungs?
Pulmonary Arteries
Which heart-wall layer contains the cardiac muscle responsible for contraction?
Myocardium
A heart rate is 75 beats/min and stroke volume is 80 mL/beat. What is the cardiac output?
6 L/min (75 bpm x 80 mL/beat = 6,000 mL/min)
Which structure allows fetal blood to pass from the right atrium to the left atrium?
Foramen ovale
What is the main function of plasma cells?
Secreting antibodies
Which type of hypersensitivity develops over several days, such as poison ivy contact dermatitis?
Type IV (Delayed)
Which antibody class is generally the first released during a primary immune response?
IgM
Which gas is required by cells for aerobic cellular respiration?
Oxygen
What happens to the diaphragm during inhalation?
It contracts and moves downward
What is the main function of the alveoli?
Exchange gases between the air and blood
What is the main function of the respiratory system?
To exchange oxygen and carbon dioxide
Which structure prevents food from entering the trachea during swallowing?
Epiglottis
A patient develops a blockage in a blood vessel supplying the lungs because a clot fragment travels through the bloodstream and becomes lodged here. What condition has occurred?
Pulmonary embolism
What is the main function of fibrin in blood clotting?
Form a mesh that strengthens and stabilizes the blood clot
What occurs during the vascular spasm phase of hemostasis?
The damaged blood vessel constricts to reduce blood flow
During blood coagulation, what does thrombin do?
Converts fibrinogen into fibrin
Which type of white blood cell is specifically involved in fighting parasitic infections and participating in allergic reactions?
Eosinophil
What is the main function of white blood cells?
Protect the body against infections and foreign substances
What is the main function of platelets during hemostasis?
Help form a platelet plug and promote blood clotting
Which white blood cells are mainly responsible for producing antibodies?
B Lymphocytes
Which type of white blood cell is most abundant in the blood and is usually the first to respond to bacterial infection?
Neutrophil
What is the difference between a thrombus and an embolus?
A thrombus is an attached clot, while an embolus travels through the bloodstream