Chapter 17 - Transfusion Reaction Review Questions

What component is most frequently involved with transfusion-associated sepsis?

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a. Plasma

b. Packed RBCs

c. Platelets

d. Whole blood

platelets

Fatal transfusion reactions are mostly caused by:

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a. Serologic errors

b. Improper storage of blood

c. Clerical errors

d. Improper handling of blood

clerical errors

Early manifestation of an acute hemolytic transfusion reaction can be confused with:

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a. Allergic reaction

b. Febrile nonhemolytic reaction

c. Anaphylactic shock

d. Sepsis

febrile nonhemolytic reaction

Pain at infusion site and hypotension are observed with what type of reaction?

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a. Delayed hemolytic transfusion reaction

b. Acute hemolytic transfusion reaction

c. Allergic reaction

d. Febrile nonhemolytic reaction

acute hemolytic transfusion reaction

Irradiation of blood is performed to prevent:

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a. Febrile nonhemolytic transfusion reaction

b. Delayed hemolytic transfusion reaction

c. Transfusion-associated graft-versus-host disease

d. Transfusion-associated circulatory overload

transfusion-associated graft-versus-host disease

The only presenting sign most often accompanying a delayed hemolytic transfusion reaction is:

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a. Renal failure

b. Unexplained decrease in hemoglobin

c. Active bleeding

d. Hives

unexplained decrease in hemoglobin

Which transfusion reaction presents with fever, maculopapular rash, watery diarrhea, abnormal liver function, and pancytopenia?

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a. Transfusion-associated sepsis

b. Transfusion-associated acute lung injury

c. Transfusion-associated graft-versus-host disease

d. Transfusion-associated allergic reaction

transfusion-associated graft-versus-host disease

A suspected transfusion-related death must be reported to:

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a. AABB

b. Food and Drug Administration (FDA)

c. College of American Pathologists (CAP)

d. The Joint Commission (TJC)

FDA

Nonimmune hemolysis can be caused during transfusion by:

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a. Use of a small bore size needle

b. Use of an infusion pump

c. Improper use of a blood warmer

d. All of the above

all of the above

Transfusion reactions are classified according to:

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a. Signs or symptoms presenting during or after 24 hours

b. Immune or nonimmune

c. Infectious or noninfectious

d. All of the above

all of the above

With febrile nonhemolytic transfusion reactions:

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a. They are self-limited

b. Fever resolves within 2-3 hours

c. Treatment is required

d. A and B are correct

e. All of the above

A and B are correct

Absolute IgA deficiency is a classic example of a severe allergic reaction. A result indicating an absolute IgA deficiency is:

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a. <0.05 mg/dL

b. <0.50 mg/dL

c.<0.50 gm/dL

d. <5 mg/dL

<0.05 mg/dL

How are mild allergic transfusion reactions with isolated symptoms or hives and urticaria treated?

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a. Transfusion is stopped and transfusion reaction workup is initiated

b. Transfusion is stopped and antihistamines administered; when symptoms improve, transfusion is restarted

c. Stop transfusion and prepare washed red cells

d. Continue transfusion with a slower infusion rate

transfusion is stopped and antihistamines administered; when symptoms improve, transfusion is restarted

TRALI presents with the following symptoms:

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a. Respiratory distress

b. Severe hypoxemia and hypotension

c. Fever

d. All of the above

all of the above

Which of the following is characteristic of iron overload?

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a. Delayed, nonimmune complications occur

b. Chelating agents are used

c. Multiorgan damage may occur

d. All of the above

all of the above