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Decline in max HR / VO2 max
smaller aerobic workload
Stiffer, less compliant vasc tissues
high BP
slower ventricle filling time w/ reduced CO
Loss of cells from sinoatrial node
slower HR / lower max HR
DEC excitability
Reduced contractility of vasc walls
slower HR
lower max VO2
small aerobic workload possible
Thickened basement membrane in capillary
reduced arteriovenous O2 uptake