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List the overall functions of the integumentary system.
Protection/barrier (mechanical, chemicals, radiation, temperature, pathogens); thermoregulation; waste excretion; vitamin D production; sensory input
What does the integumentary barrier protect against?
Mechanical damage, chemicals, radiation, temperature extremes, pathogens
How does the integument help with thermoregulation?
Blood reservoir (5%); vasodilation/vasoconstriction; sweat glands
What is skin (the cutaneous membrane) and how thick is it?
Cutaneous membrane; 0.5 mm on eyelids to 4 mm on heels; mostly 1–2 mm elsewhere
What is the integument?
Skin + subcutaneous layer (hypodermis)
Epidermis: tissue type and blood supply
Keratinized stratified squamous epithelium; avascular
Stratum corneum
Surface layer of the epidermis; callus and dandruff
Stratum lucidum
Found in thick skin only
Stratum granulosum
Cells contain keratohyalin and lamellar granules
Stratum spinosum
Cells contain prekeratin filaments
Stratum basale
Deepest epidermal layer; mitotic stem cells and melanocytes
Dermis: blood supply and contents
Vascularized; accessory organs (glands, hair follicles, arrector pili muscles, nail roots)
Papillary region of the dermis
Top 1/5 of the dermis; areolar connective tissue
Reticular region of the dermis
Bottom 4/5 of the dermis; dense irregular connective tissue
Is the hypodermis (subcutaneous layer) a true layer of the skin?
Not a true layer of the skin
Tissues of the hypodermis
Adipose CT and areolar CT (contains Pacinian corpuscles)
Functions of the hypodermis
Support; binds dermis to underlying tissues; adipose storage; cushioning; insulation
Function of hairs (pili)
Protection; reduce heat loss; sense light touch
Function of the arrector pili muscle
Smooth muscle that causes goosebumps; aids thermoregulation
Function of the hair root plexus
Neuron dendrites wrap each hair follicle to detect hair movement
Overall functions of skin glands
Excretion; thermoregulation; secretion of sebum, sweat, and cerumen
Functions of nails
Grasp and manipulate objects; protect distal ends of digits; scratching; support and counter pressure to the palmar surface of the finger
Types of sensations detected by skin sensory receptors
Touch, pressure, temperature, tickle, itch, pain
Name the three types of skin glands
Sebaceous (oil); sudoriferous (sweat); ceruminous
Sebaceous glands: location and product
Typically connected to hair follicles; secrete sebum
Function of sebum
Prevents dehydration of hair and skin; inhibits growth of certain bacteria
Type of secretion used by sebaceous glands
Holocrine
Which gland type is associated with acne?
Sebaceous glands
Two types of sudoriferous (sweat) glands
Eccrine (merocrine) and apocrine
Ceruminous glands: product and secretion type
Cerumen; holocrine
Name the five sensory receptors of the integument
Hair root plexuses; Merkel's discs; free nerve endings; Meissner's corpuscles; Pacinian (lamellated) corpuscles
Hair root plexus: function and location
Senses hair movement; hair follicle (dendrites wrap each hair)
Merkel's discs: function and location
Sustained touch/pressure; stratum basale
Free nerve endings: function and location
Warmth, coolness, pain, tickling, itching; papillary/epidermal region
Meissner's corpuscles: function and location
Light touch and tickle; dermal papillae
Meissner's corpuscles are also called
Corpuscles of touch
Pacinian corpuscles: function and location
Deep pressure; deep reticular dermis or hypodermis
Pacinian corpuscles are also called
Lamellated corpuscles
Four cell types of the epidermis
Keratinocytes; melanocytes; macrophages (Langerhans cells); tactile epithelial cells (Merkel's discs)
Keratinocytes: percentage and function
90%; main structural cell of the epidermis
Melanocytes: percentage, function, location
1%; produce melanin for skin color and UV protection; stratum basale
Macrophages (Langerhans cells): percentage and function
8%; immune defense in the epidermis
Tactile epithelial cells (Merkel's discs): percentage and function
1%; sustained touch/pressure sensory receptors
Thin skin: epidermis thickness
75–150 μm
Thick skin: epidermis thickness
400–600 μm
Thin skin: stratum corneum and stratum lucidum
Thin corneum; no lucidum
Thick skin: stratum corneum and stratum lucidum
Thick corneum; has lucidum
Structures found in thin skin
Hair, sebaceous glands, and sweat glands
Structures found in thick skin
Many sweat glands; lacks hair and sebaceous glands
Where is thin skin found?
Everywhere there is a cutaneous membrane where thick skin is not present
Where is thick skin found?
Palms (palmar), soles (plantar), digits (volar surface)
Function of thick skin
Protection against friction and wear
Name the three pigments contributing to skin color
Melanin; carotene; hemoglobin
Melanin: color range and what it forms
Pale yellow to red to tan to black; accumulation causes freckles and moles
Carotene: color and location
Yellow to orange; concentrates in stratum corneum; most visible in palms and soles
Hemoglobin: color and what determines its effect
Red; dermal vascularization, vasoconstriction, and vasodilation
Hair shaft
Visible region above the skin surface
Hair root
Region below the skin surface, penetrating into the dermis/hypodermis
Hair bulb
Enlarged base at the bottom of the root
Hair follicle
Epithelial root sheath surrounded by a dermal root sheath
Hair accessory structures
Arrector pili muscle; hair root plexus; sebaceous glands
Eponychium (cuticle)
The stratum corneum of the epidermis
Nail matrix
Epithelium proximal to the nail root with dividing cells that produce new nail cells