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Acute Coronary Syndromes
All cases will start out with the patient receiving a 12 lead EKG to classify patient into 1 of 3 EKGs
- ST-segment elevation suggesting current injury
- ST-segment depression suggesting ischemia
- Nondiagnostic or normal EKG
Key Components of ACS
Identification, assessment and triage of acute ischemic chest discomfort
Initial treatment of possible ACS
Emphasis on early reperfusion of the patient with ACS/STEMI
Early Treatment Priorities ACS
Rapid Reperfusion
Relief of ischemic pain
Treatment of early life-threatening complications
Drugs used to relieve discomfort of ACS:
Oxygen
Aspirin
Nitroglycerin
Morphine
Fibrinolytic Therapy
Heparin
What arrhythmia most likely to develop during first 4 hours after onset of symptoms?
VF
Program Development Needed in Communities for ACS to:
Recognize symptoms of ACS
Activation of EMS
Early CPR
Early Defibrillation
Public AEDs
Coordinated System between EMS, ED, and Cardiac Team
Primary Goals of Therapy for ACS
Identification of patients with STEMI and triage for reperfusion
Relief of ischemic chest pain
Prevention of MACE: (Major Adverse Coronary Event)
Treatment of acute, life-threatening complications of ACS, such as VF/Pulseless VT, Symptomatic Bradycardias, and unstable tachycardias
Symptoms suggestive of ischemia or infarction?
Chest pain is number #1
Pressure or fullness in center of chest
Shoulder, neck, arm, jaw pain
Pain in back between shoulder blades
Light-headedness, dizziness, fainting, sweating, nausea, vomiting
Sudden SOB
Obtain 12 lead EKG -
Providing EKG while in route to hospital along with interpretation will help mobilize the hospitals cardiac team to respond to STEMI
STEMI
ST Elevation

High Risk NSTEMI
ST depression or T wave inverse

Minutes after heart attack starts:
ST shifts
Hours later of Heart attack
ST shifted
R dropping
Q appears to be noticeable
1-2 days after Heart Attack
T inverted
Q goes lower
Several days after Heart Attack
ST Normal
T inverted
Weeks after the attack
ST and T normal
Q no change
Intermediate Low Risk
Normal EKG
Clot Busters Examples are
are rtPA (Recombinant Tissue Plasminogen Activator) , reteplase, tenecteplase, and streptokinase
Fibrinolytic Therapy
Should be administered within 30 minutes of patient's arrival to ER.
If no contraindications - F.T. should be administered within 12 hours of onset of symptoms. Not recommended for those over 12 hours. Do NOT give in those greater that 24 hours after
Percutaneous coronary intervention (PCI) is?
Stent Placement is most common
Used in those that fail to reperfuse with fibrinolytics and if it can be done in less than 90 minutes from first medical contact
Which is superior PCI or fibrinolytic therapy?
PCI
- Transfer to a PCI facility may be more important that to a fibrinolytic only facility
Other Treatments for ACS
IV nitro
Heparin
B-Blockers
ACE Inhibitors
Statins
Defibrillation:
Shock used during a code situation
Cardioversion:
Synchronized shock that is conducted only during the R wave of the QRS. Usually planned. (SVT)
Transcutaneous Pacing
Delivers an electrical stimulus for electrical depolarization and cardiac contraction (during bradycardia or blocks)
Symptomatic Bradycardia:
HR < 50/min
Heart rate is slow
Patient symptoms for Bradycardia
Chest pain
SOB
Decreased LOC
Weakness/fatigue
Dizziness
Syncope
- The symptoms are due to the slow rate
What to do for a stable bradycardia?
Monitor
What to do for an unstable bradycardia?
1. Atropine first
2. Dopamine
3. Epi Drip
4. Pacing
Signs of Bradycardia
Hypotension
Sudden Drop in BP
Diaphoresis
CHF
Pulmonary Edema
PVCs
Persistent Bradycardia causing:
Hypotension?
Acutely altered mental status?
Signs of shock?
Ischemic chest discomfort?
Acute heart failure?
Atropine
1 mg bolus ; max 3 mg
Dopamine
5-20 mcg/kg
Epinephrine IV infusion
2-10 mcg per minute infusion. Titrate to patient response.
Transcutaneous Pacing is?
Delivers an electrical stimulus for electrical depolarization and cardiac contraction (during bradycardia or blocks)
- Most defibrillators now have a pacing device
- Conscious patients will need pain control
Pacing impulses delivered to the heart through:
the skin with cutaneous electrodes
Indications for use include of Pacing is:
symptomatic Bradycardia that is unstable
Contraindicated of Pacing in:
severe hypothermia and asystole
Tachycardia
HR >100
Answer these questions when determining Tachy:
Are symptoms present or absent
Is the patient stable or unstable
Is the QRS narrow or wide
Is the rhythm regular or irregular
Is the QRS monomorphic or polymorphic
Stable Tachy
HR >100
No significant signs or symptoms
Underlying cardiac abnormality that generates the rhythm
If the patient is stable/non symptomatic tachy, do not:
Do not cardiovert
If shock is given, it could actually increase the HR in a stable tachy.
Unstable Tachy
Tachyarrhythmias - HR > 100/min
Symptomatic Tachyarrhythmia
HR >100/min with signs and symptoms due to the rapid HR
Beating so fast that CO is reduced can be caused by
pulmonary edema, coronary ischemia, reduced blood flow
Beating ineffectively so that coordination between the atrium and ventricles reduces:
CO
Symptoms and Signs of Unstable Tachy
Hypotension
Acutely Altered Mental Status
Signs of Shock
Ischemic Chest Discomfort
Acute Heart Failure
Must be able to recognize 2 key things quickly for unstable tachy:
1. Patient is significantly symptomatic or unstable
2. Signs and symptoms are caused by the tachy
What to do for a Stable Tachy?
Vagal maneuver
Adenosine
Beta-blockers
Wide QRS >12 seconds indicate for:
Adenosine (if regular)
Adenosine
1st: 6 mg rapid IV push
2nd: 12 mg
Procainamide
20-50 mg/min
Amiodarone
150 mg
Prior to a Cardioversion, what do you do?
Get IV access and sedate the patient
Synchronized Cardioversion
uses a sensor to deliver a shock that is synchronized with a peak of a QRS complex. Press the SHOCK button, delay may occur until the defibrillator catches a R wave in a QRS. This avoids shock during repolarization (T wave) which could lead to Vfib.
When is shock delivered for synchronized cardioversion?
When it catches the R wave of QRS
Defibrillation Shock
Electrical shock will be delivered as soon as the operator pushes the SHOCK button. The shock will fall randomly anywhere in the cardiac cycle. They should use higher energy levels than synchronized cardioversion
When is shock delivered for Defib?
Delivered right as soon as operator pushes SHOCK, it'll fall anywhere in cardiac cycle
Potential Problems with Synchronization:
- If the R waves have low amplitude, the sensor may not be able to identify and will not deliver the shock
- Some cardioversion machines will not synchronize through the quick paddles which some rescuers may not realize
- Synchronization can take extra time (attaching electrodes, being unfamiliar with the equipment, catching the R wave)
When to Use Synchronized Cardioversion?
Unstable SVT
Unstable AFib
Unstable AFlutter
Unstable regular monomorphic tachy with pulse
When to use Defibrillation/Shock?
Pt is Vfib or Pulseless VTach
Pre-arrest deterioration when a delay in converting could result in arrest
Energy level Unstable AFib
200J
Energy level Unstable Monomorphic VT
100J
Energy level Unstable SVT
200J
Energy level Unstable Polymorphic VT
Defibrillation high dose shock (Treat as VF)
Ischemic Strokes
87% of strokes - usually caused by an occlusion of an artery to a region of the brain
Hemorrhagic Stroke
13% of strokes - blood vessel in the brain suddenly ruptures into the surrounding tissue
The goal of stroke care is
to minimize brain injury and maximize the patient's recovery
Stroke Chain of Survival
Rapid recognition and reaction to stroke warning signs
Rapid EMS dispatch
Rapid EMS system transport and prearrival notification to receiving hospital
Rapid diagnosis and treatment in the hospital.
The 8 D's of Stroke Care
Detection - Recognition of stroke
Dispatch - Early Activation
Delivery - Rapid EMS identification and transport
Door - Triage to stroke center
Data - Rapid evaluation within the ER
Decision - Stroke expertise & therapy selection
Drug/Device - Fibrinolytic or Endovascular
Disposition - Admission to stroke unit
Critical Time Intervals: 10 Mins
Immediate General Assessment
Critical Time Intervals: 20 Mins
Immediate Neuro Assessment & CT
Critical Time Intervals: 45 Mins
Interp of CT
Critical Time Intervals: 60 Mins
Admin of Fibrinolytic Therapy timed from ER arrival
Critical Time Intervals: 3 hours
Admin of Fibrinolytic Therapy timed from onset of symptoms
Critical Time Intervals: 6 hours
Admin of Endovascular Therapy timed from onset of symptoms
Warning Signs & Symptoms of Stroke:
Sudden weakness or numbness of face, arm, leg (doesn't have to be all 3)
Sudden confusion
Trouble speaking or understanding
Sudden trouble seeing in one or both eyes
Sudden trouble walking
Dizziness or loss of balance or coordination
Sudden severe headache with no known cause
If stroke is suspected:
activate EMS immediately, TIME IS CRITICAL!
Cincinnati Prehospital Stroke Scale
Facial droop, arm drift, abnormal speech
Facial Droop
have patient smile to show teeth
Abnormal - one side of face does not move as well as the other
Arm Drift
Close eyes, extend both arms straight out, palms up for 10 seconds
Abnormal - One arm does not move or drifts down compared with the other arm
Abnormal speech
Patient say "you can't teach an old dog new tricks"
Abnormal - Patient slurs words, uses wrong words, or unable to speak
If any 1 of the 3 signs:
is abnormal, the probability of a stroke is 72%
Fibrinolytic Therapy Candidate
Less than 3 hours of onset of symptoms
Ischemic stroke causing deficit
Older than 18 years
If patient accepts for Fibrinolytic Therapy:
Start rtPA therapy (alteplase)
Do not give anticoagulants for 24 hours
Not a Fibrinolytic Therapy Candidate
Head Trauma
Intracranial Hemorrhage
Elevated BP Systolic > 185 or Diastolic > 110
Active bleeding
Low platelets
Use of Heparin within 48 hours
Extended rtPA Window
3-4.5 hours
- Although outcomes are not as good, evidence shows that some stroke patients may benefit from receiving rtPA even if the 3 hour mark has passed, up to 4.5 hours.
Candidate for Extended rtPA Window:
ischemic stroke is present
onset of symptoms is 3-4.5 hours
Non Candidate for Extended rtPA Window:
Age is >80 years
Severe stroke
Taking oral anticoagulants
History of both diabetes and prior stroke
General Stroke Care
Stroke Pathway
- Admit to stroke unit and monitor BP and Neuro status
Support Airway, Breathing, Circulation
Monitor Glucose (insulin for Glucose > 185)
Monitor Temp
Dysphagia Screening
Monitor Adverse reactions to fibrinolytic therapy
Transfer to ICU if needed
Fibrinolytic Therapy Adverse Effects
Hypertension
Seizures
Intracranial Hemorrhage (High ICP)
Other bleeding complications
Hypotension from blood loss
Hypertension Management
Manage hypertension with medications such as Labetalol, Nicardipine, etc.
Goal is to keep BP below 185/110 so that patient is a candidate for rtPA
Cardiac Arrest in Pregnancy
Continuous lateral uterine displacement to move the baby to left side to help with CPR
Cardiac Arrest wtih Opioids
Give narcan
Make sure the patient has a patent airway