PNA treatments

outpatient tx for typical CAP no comorbidities

amoxicillin

outpatient tx for atypical CAP no comorbidities

Augmentin + doxy

outpatient tx for CAP, no comorbidities, PCN allergy

Augmentin + doxy

outpatient tx for CAP with comorbidities

augmentin + azithromycin

alternative tx for CAP outpatient tx with comorbidities

augmentin + doxy

outpatient CAP tx with comorbidities and PCN allergy

levo

inpatient CAP tx no MRSA or PSUEDO risk

Ceftriaxone + azithromycin

inpatient CAP tx no MRSA or PSUEDO risk alternative

Ceftriaxone + doxy

inpatient CAP tx no MRSA or PSUEDO risk PCN allergy

levo

what do you add for MRSA coverage

vancomycin

what do you add for PSUEDO coverage

cefepime or zosyn + atypical coverage

what do you add for both MRSA and pseudo coverage?

cefepime + vance + azithromycin

s. pneumoniae tx

amoxicillin / Ceftriaxone

mycoplasma tx

azithromycin / doxy

H. influenzae tx

augmentin / ceftriaxone

klebsiella tx

Ceftriaxone

legionella tx

Azithromycin or levofloxacin

HAP/VAP with MDR risk factor tx

piperacillin-tazo + vancomycin + levo

OR

cefepime + vancomycin + levo

initial aspiration pneumonia tx

airway suction + O2 +/- ventilation

outpatient aspiration pneumonia tx

augmentin

inpatient aspiration pneumonia tx

ampicillin

alternative aspiration pneumonia tx

metronidazole + amoxicillin

OR metronidazole + penicillin G

tx of mild active PCP

PO bactrim

tx of moderate active PCP

IV bactrim + PO prednisone

tx of severe active PCP

IV bactrim + IV methylprednisolone

alternative tx for PCP

- Trimethoprim + dapsone

- Primaquine + clindamycin

- Atovaquone

- Pentamidine

PCP prophylaxis

Bactrim

blastomycosis tx step 1

IV amphotericin B 1-2 weeks until clinical improvement

blastomycosis tx step 2

transition to oral itraconazole

first line tx for aspergillus

PO voriconazole

second line tx for aspergillus

PO itraconazole