Approved Indication(s)

Generic (Brand)

• osteoporosis in post-menopausal women

• glucocorticoid-induced osteoporosis

• Paget’s disease

• increase bone mass in men w/ osteoporosis

Alendronate Sodium (Fosamax)

• osteoporosis in post-menopausal women

• reduction in risk of invasive breast cancer in post-menopausal women w/ osteoporosis/high risk for invasive breast cancer

Raloxifene HCl (Evista)

• various bacterial infections

• gonorrhea

• acute uncomplicated urethral/anogenital infection

Amoxicillin Trihydrate (Amoxil, Moxatag, & Trimox)

• sinusitis

• otitis media

• lower respiratory tract infection

• SSSI

• UTI

• CA pneumonia

Amoxicillin with Clavulanate Potassium (Augmentin & Augmentin XR)

• mild to moderate lower/upper respiratory tract infection

• SSSI

• acute bacterial exacerbation of COPD

• acute bacterial sinusitis

• genital ulcer disease

• urethritis/cervicitis

• acute otitis media

• pharyngitis/tonsilitis

• CA pneumonia

• pelvic inflammatory disease

Azithromycin Dihydrate (Zithromax & Zmax)

• CA pneumonia in adults

• acute bacterial exacerbation of chronic bronchitis in adults

• acute maxillary sinusitis

• pharyngitis/tonsilitis

• uncomplicated SSSI

• acute bacterial otitis media in children

Cefdinir (Omnicef)

• various bacterial infections

• streptococcal pharyngitis

• SSSI

• uncomplicated cystitis in patients over 15 years of age

Cephalexin Monohydrate (Keflex)

• infectious diarrhea

• UTI

• acute uncomplicated pyelonephritis

• lower respiratory tract infection

• SSSI

• bone/joint infection

• typhoid fever

• uncomplicated cervical/urethral gonorrhea

• acute uncomplicated cystitis in females

• complicated intra-abdominal infection

Ciprofloxacin HCl (Cipro & Cipro XR)

• serious respiratory tract infection

• SSSI

• soft tissue infection

• septicemia

• intra-abdominal infection

• female pelvis/genital tract infection

Clindamycin HCl (Cleocin)

• various bacterial infections

• primary/secondary syphilis

• uncomplicated gonorrhea

• uncomplicated urethral/endocervical/rectal infection

• prophylaxis of malaria

Doxycycline Hyclate (Vibramycin & Doryx)

• acute bacterial exacerbation of chronic bronchitis

• CA/nosocomial pneumonia

• chronic bacterial prostatitis

• acute bacterial sinusitis

• uncomplicated/complicated SSSI

• uncomplicated/complicated UTI

• acute pyelonephritis

Levofloxacin (Levaquin)

• various bacterial infections

• syphilis

• gonorrhea

• uncomplicated urethral/endocervical/rectal infection

• inflammatory lesions

• non-nodular moderate to severe acne vulgaris in patients 12 years of age & older

Minocycline HCl (Minocin, Dynacin, & Solodyn ER)

• impetigo

• nasal cavity infection

• traumatic skin lesion infection

Mupirocin (Bactroban)

• ophthalmic infections associated with corneal ulcers or conjunctivitis

Ofloxacin (Ocuflox)

• UTI

• shigellosis

• acute exacerbation of chronic bronchitis in adults

• acute otitis media in children

• PCP

• traveler’s diarrhea in adults

Sulfamethoxazole with Trimethoprim (Bactrim & Septra)

• hormone receptor-positive early breast cancer in post-menopausal women

• hormone receptor-positive/hormone receptor-unknown locally advanced or metastatic breast cancer in post-menopausal women

• advanced breast cancer in post-menopausal women with disease progression following alternative therapy

Anastrozole (Arimidex)

• metastatic breast cancer in men/post-menopausal women

• delaying recurrence of breast cancer following total mastectomy & axillary dissection in post-menopausal women

• reduction in breast cancer incidence in high-risk women

Tamoxifen Citrate (Nolvadex)

• gestational cancers

• advanced stage non-Hodgkin’s lymphomas

• breast cancer

• epidermoid cancers of the head/neck

• advanced mycosis fungoides

• non-metastatic osteosarcoma

• lung cancer

• prophylaxis of meningeal leukemia

• symptomatic control of severe, recalcitrant, disabling psoriasis

• management of severe, active RA in adults

• management of active polyarticular-course juvenile RA in children

Methotrexate (Trexall)

• various allergic/inflammatory diseases including cerebral edema

• trichinosis w/ neurologic/myocardial involvement

• induce the diuresis/remission of proteinuria in the nephrotic syndrome

• symptomatic relief of ulcerative colitis/regional enteritis during critical periods

• maintenance/during flare-ups of systemic lupus, erythematosus, polymyositis, or rheumatic carditis

• palliative management of leukemias & lymphomas

• various anemias/thrombocytopenia

• various endocrine/respiratory disorders

Dexamethasone (Decadron)

• various allergic/inflammatory disease

• adjunctive therapy in tuberculous meningitis

• trichinosis w/ neurologic/myocardial involvement

• induce the diuresis/remission of proteinuria in the nephrotic syndrome

• symptomatic relief of ulcerative colitis/regional enteritis during critical periods,

• maintenance/during flare-ups of systemic lupus, erythematosus, polymyositis, or rheumatic carditis

• palliative management of leukemias & lymphomas

• various anemias/thrombocytopenia

• various endocrine/respiratory disorders

Methylprednisolone (Medrol)

• various allergic/inflammatory disease

• adjunctive therapy in tuberculous meningitis

• trichinosis w/ neurologic/myocardial involvement

• induce the diuresis/remission of proteinuria in the nephrotic syndrome

• symptomatic relief of ulcerative colitis/regional enteritis during critical periods,

• maintenance/during flare-ups of systemic lupus, erythematosus, polymyositis, or rheumatic carditis

• palliative management of leukemias & lymphomas

• various anemias/thrombocytopenia

• various endocrine/respiratory disorders

Prednisone (Deltasone)

• UTI

  • acute uncomplicated UTI

Nitrofurantoin (Macrodantin, Macrobid, & Furadantin)

• acute intestinal/liver abscess amebiasis

• bacterial vaginosis

• asymptomatic/symptomatic trichomoniasis

• anerobic bacteria infection

• surgical prophylaxis in colorectal surgery

Metronidazole (Flagyl)

• HTN

• chronic stable/vasospastic angina

Amlodipine Besylate (Norvasc)

• HTN

  • maintenance

Amlodipine Besylate with Benazepril HCl (Lotrel)

• HTN

  • maintenance

Prazosin HCl (Minipress)

• angina pectoris due to coronary artery spasm/chronic stable angina

• HTN

• control of atrial fibrillation/atrial flutter and rapid conversion of paroxysmal supraventricular tachycardias to sinus rhythm

Diltiazem HCl (Cardizem (CD), Cartia, Dilacor, Dilt-XR, Tiazac)

• essential HTN

Hydralazine HCl (Apresoline)

• HTN

• BPH

Terazosin HCl (Hytrin)

• signs & symptoms of allergic conjunctivitis

• ocular itching associated w/ allergic conjunctivitis

Olopatadine HCl (Patanol, Pataday, & Pazeo)

• allergic conjunctivitis

• acne rosacea

• superficial punctate keratitis

• herpes zoster keratitis

• iritis

• cyclitis

• selected infective conjunctivitis

Prednisolone Acetate (Pred Forte, Pred Mild, & Omnipred)

• bronchoconstriction in patients with COPD including chronic bronchitis & emphysema (long-term maintenance)

Arformoterol (Brovana)

• bronchospasm associated with COPD, including chronic bronchitis & emphysema (maintenance)

• rhinorrhea associated with allergic & nonallergic perennial rhinitis in patients over the age of 12 years

• rhinorrhea associated with the common cold in patients over the age of 12 years

Ipratropium Bromide (Atrovent)

• bronchospasm associated w/ COPD in patients requiring more than 1 bronchodilator

Ipratropium Bromide with Albuterol Sulfate (Combivent & DuoNeb)

• bronchospasm associated w/ COPD, including chronic bronchitis & emphysema and for reducing exacerbations (long-term, once daily, maintenance)

Tiotropium Bromide (Spiriva)

• COPD, including chronic bronchitis or emphysema (maintenance)

Umeclidinium Bromide (Incruse Ellipta)

• airflow obstruction in patients w/ COPD (long-term, once daily, maintenance)

Umeclidinium and Vilanterol (Anoro Ellipta)

• asthma & as prophylactic therapy in patients 12 months & older (maintenance)

Budesonide (Pulmicort)

• asthma as prophylactic therapy (maintenance)

• patients receiving systemic steroids

Fluticasone Propionate (Flovent)

• prophylaxis & chronic treatment of asthma in adults & children 2 years of age and older

• relief of symptoms of seasonal allergic rhinitis for adults & children 2 years of age and older

• perennial allergic rhinitis in adults & pediatric patients 6 months of age and older

• prevention of exercise-induced bronchoconstriction in patients 15 years of age & older

Montelukast Sodium (Singulair)

• asthma in patients 12 years of age & older

• airflow obstruction in patients with COPD, including chronic bronchitis & emphysema (maintenance)

Budesonide and Formoterol Fumarate Dihydrate (Symbicort)

• airflow obstruction in patients with COPD, including bronchitis & emphysema (long-term, one-daily, maintenance)

• reduce exacerbations of COPD in patients with a history of exacerbations

• asthma in patients 18 years of age & older (once-daily)

Fluticasone Furoate and Vilanterol (Breo Ellipta)

• asthma for certain ages (long-term maintenance)

• airflow obstruction in patients w/ COPD associated w/ chronic bronchitis (maintenance)

Fluticasone Propionate with Salmeterol Xinafoate (Advair)

• asthma in patients 18 years & older (maintenance)

• COPD (maintenance)

Fluticasone Furoate, Umeclidinium Bromide, and Vilanterol (Trelegy Ellipta)

• relief of bronchospasm in patients w/ reversible obstructive airway disease

• maintenance to prevent exacerbations of bronchospasm

• prevention of exercise-induced bronchospasm

Albuterol Sulfate (Proventil, Ventolin, & Proair)

• relief of bronchospasms in adults & children 6 years of age and older w/ reversible obstructive airway disease

Albuterol Sulfate (Proventil)

• relief of the symptom complex of tension (or muscle contraction) HA

Butalbital, Acetaminophen, and Caffeine (Fioricet)

• management of moderate to moderately severe pain IN or NOT in patients who require ATC treatment for an extended period of time

Tramadol HCl (Ultram & Ultram ER)

• symptomatic BPH in men with enlarged prostate gland to improve symptoms

• reduce risk of acute urinary retention

• reduce risk of the need for BPH-related surgery

Dutasteride (Avodart)

• symptomatic BPH

• reduce risk of symptomatic progression of BPH

Finasteride (Proscar)

• HTN alone or in combination with thiazide diuretics

Benazepril HCl (Lotensin)

• HTN

• CHF

• asymptomatic left-ventricular dysfunction

Enalapril Maleate (Vasotec & Epaned)

• HTN alone or in combination with thiazide diuretics

• management of HF as adjunctive therapy when added to conventional therapy including diuretics or digitalis

Fosinopril Sodium (Monopril)

• HTN

• adjunctive therapy in the management of CHF in patients NOT responding adequately to diuretics & digitalis

• hemodynamically stable patients w/in 24 H of acute MI

Lisinopril (Prinivil & Zestril)

• HTN

Lisinopril with HCTZ (Zestoretic & Prinizide)

• HTN

Losartan Potassium with HCTZ (Hyzaar)

• HTN

Olmesartan Medoxomil (Benicar)

• HTN alone or in combination with thiazide diuretics

• reduce risk of MI, stroke, & death from cardiovascular causes

• heart failure in post-MI patients

Ramipril (Altace)

• HTN

• diabetic nephropathy with an elevated SrCr & proteinuria in patients with TD2 & HTN

Irbesartan (Avapro)

• HTN

• reduce risk of stroke in patients with HTN & left-ventricular hypertrophy

• diabetic nephropathy with an elevated SrCr & proteinuria in patients with TD2 & HTN

Losartan Potassium (Cozaar)

• HTN

• reduce risk of MI, stroke, or death in cardiovascular causes in patients 55 years of age or older at high risk & who are unable to take ACE inhibitors

Telmisartan (Micardis)

• HTN when used alone or in combination with other antihypertensive agents

• heart failure in patients who are intolerant of ACE inhibitors

• reduce cardiovascular mortality following MI in patients with left-ventricular failure or dysfunction

Valsartan (Diovan)

• signs & symptoms of BPH

Alfuzosin HCl (Uroxatral)

• signs & symptoms of BPH

Tamsulosin HCl (Flomax)

• moderate to severe vasomotor symptoms associated with menopause

• vulval & vaginal atrophy

• hypoestrogenism due to hypogonadism, castration, or primary ovarian failure

• Estradiol (Vivelle-Dot, Alora, Climara, Estrace, Divigel, Femring, Estring, & Vagifem)

• Estradiol (Estrace)

• vasomotor symptoms associated with menopause

• female hypogonadism

• female castration & primary ovarian failure

• breast cancer

• prostatic carcinoma

• prevention of postmenopausal osteoporosis after other non-estrogen treatments have been considered

• abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology

Estrogens, Conjugated (Premarin)

• replacement therapy for reduced or absent thyroid function of any etiology

• myxedema coma or stupor without severe heart disease

Levothyroxine Sodium (Synthroid, Levoxyl, & Levothroid)

• mild hypothyroidism

• myxedema

• congenital hypothyroidism

• simple (non-toxic) goiter

• myxedema coma

Liothyronine Sodium (Cytomel & Triostat)

• abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology

• secondary amenorrhea

• producing an optimum secretory transformation of an endometrium that has been adequately primed with either endogenous or exogenous estrogen

• reduction of endometrial hyperplasia in post-menopausal women receiving 0.625 mg conjugated estrogens for 12 to 14 consecutive days per month, either beginning on the 1st day of the cycle or the 16th day of the cycle

Medroxyprogesterone Acetate (Provera)

• prevention of endometrial hyperplasia in non-hysterectomized post-menopausal women who are receiving conjugated estrogen tablets

Progesterone (Prometrium)

• replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone including primary hypogonadism & hypogonadotropic hypogonadism

Testosterone Gel (Androgel, Fortesta, & Testim)

• adult hypothyroidism of any etiology

• congenital hypothyroidism (children)

• treatment/prevention of various types of euthyroid or multinodular goiters, including thyroid nodules, sub-acute or chronic lymphocytic thyroiditis and in the management of thyroid cancer

• myxedema coma

• thyroid suppression therapy

Thyroid (Armour Thyroid)

• recurrent ventricular fibrillation & recurrent hemodynamically unstable ventricular tachycardia in patients who are unresponsive or cannot tolerate other antiarrhythmic agents

• treatment/prophylaxis of frequently recurring ventricular fibrillation & hemodynamically unstable ventricular tachycardia in patients refractory to other therapy & in patients unable to take it orally

Amiodarone (Cordarone, Pacerone, & Nexterone)

• conversion of atrial fibrillation & atrial flutter to normal sinus rhythm

• maintenance of normal sinus rhythm in patients with atrial fibrillation or atrial flutter of > 1 week duration who have been converted to normal sinus rhythm

Dofetilide (Tikosyn)

• prevention of paroxysmal supraventricular tachycardias associated with disabling symptoms

• prevention of paroxysmal atrial fibrillation or flutter associated with disabling symptoms

• prevention of documented life-threatening sustained ventricular tachycardia

Flecainide (Tambocor)

• documented ventricular arrhythmias

Sotalol HCl (Betapace)

• HF

• atrial fibrillation

• atrial flutter

• paroxysmal atrial tachycardia

Digoxin (Lanoxin & Digitek)

• preventative for dental caries

Sodium Fluoride Paste (SF 5000 Plus)

• insomnia

Eszopiclone (Lunesta)

• insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakening (short-term)

Temazepam (Restoril)

• insomnia (short-term)

Zolpidem Tartrate (Ambien (CR) & Intermezzo)

• insomnia (short-term)

Zaleplon (Sonata)

• reduce the risk of CV death & hospitalization for HF in adult patients with chronic heart failure

• symptomatic HF with systemic left ventricular dysfunction in pediatric patients aged 1 year & older

Sacubitril and Valsartan (Entresto)

• as an adjunct to diet to reduce elevated total cholesterol, LDL-C, apo B, & triglyceride levels and to increase HDL-C levels in patients with primary hypercholesterolemia, mixed dyslipidemia, in patients with elevated serum triglyceride levels, and in primary dysbetalipoproteinemia and in patients with multiple coronary heart disease risk factors to reduce the risk of MI, angina, and revascularization procedures

• to reduce the risk of non-fatal MI, fatal & non-fatal stroke, angina, revascularization procedures, and hospitalization for CHF in patients with clinically evident coronary heart disease

• to reduce total cholesterol & LDL-C in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments

• as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys & postmenarchal girls, 10-17 years of age, with heterozygous familial hypercholesterolemia

Atorvastatin Calcium (Lipitor)

• as an adjunct to diet for the treatment of primary hypercholesterolemia

• to slow the progression of coronary atherosclerosis in patients with coronary heart disease as part of a treatment strategy to lower total & LDL cholesterol to target levels

• for primary prevention of coronary heart disease in patients without symptomatic CVD who have average-to-moderately elevated total-C & LDL-C and below-average HDL-C

• as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys & postmenarchal girls, 10-17 years of age, with heterozygous familial hypercholesterolemia

Lovastatin (Mevacor)

• as an adjunct to diet for the reduction of elevated total & LDL cholesterol, apo-B, & triglyceride levels and to increase HDL cholesterol in patients with primary hypercholesterolemia & mixed dyslipidemia

• to reduce the risk of MI, coronary death, & myocardial revascularization procedures

• as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys & postmenarchal girls, 10-17 years of age, with heterozygous familial hypercholesterolemia

Pravastatin Sodium (Pravachol)

• as adjunctive therapy to diet to reduce elevated total-C, LDL-C, apo B, non HDL-C, & TG levels, primary dysbetalipoproteinemia, and to increase HDL-C in patients with primary hypercholesterolemia and mixed dyslipidemia

• to reduce LDL-C, total-C, & apo B in patients with homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering treatments

• as an adjunct to diet to slow the progression of of atherosclerosis by lowering total-C & LDL-C

Rosuvastatin Calcium (Crestor)

• as an adjunct to diet for the reduction of elevated total & LDL cholesterol, apo-B, & triglyceride levels and to increase HDL cholesterol in patients with primary hypercholesterolemia & mixed dyslipidemia

• to lower total & LDL-C in patients with homozygous familial hypercholesterolemia

• as an adjunct to diet to reduce total-C, LDL-C, and apo B levels in boys & postmenarchal girls, 10-17 years of age, with heterozygous familial hypercholesterolemia

Simvastatin (Zocor)

• prophylactic treatment of angina pectoris due to coronary artery disease

Isosorbide Mononitrate (Imdur)

• prophylaxis, treatment, & management of angina pectoris (SL)

• angina pectoris, perioperative HTN, CHF associated with acute MI, and for production of controlled hypotension during surgery (parental)

Nitroglycerin (Nitrostat & Nitroquick)

• chronic angina

Ranolazine (Ranexa)

• reduction in risk of stroke in nonvalvular Afib

• DVT

• PE

• reduction in the risk of recurrence of DVT & PE

• prophylaxis of DVT following hip replacement or knee replacement surgery

Rivaroxaban (Xarelto)

• prophylaxis & treatment of PE

• Afib with embolization

• prophylaxis & treatment of venous thrombosis & its extension

• adjunct in the treatment of coronary occlusion

Warfarin Sodium (Coumadin & Jantoven)

• symptomatic orthostatic hypotension

Midodrine (Proamatine)

• gout & uric acid nephropathy, with or without symptoms of gout

• prevention of uric acid nephropathy in patients undergoing vigorous therapy of neoplastic disease

• prevention of flare-up of acute gouty arthritis

• secondary hyperuricemia associated with malignancy

• recurrent calcium oxalate stones

Allopurinol (Zyloprim)

• treatment & relief of pain in attacks of acute gouty arthritis

• prophylaxis of acute gouty arthritis

• prophylaxis of an acute gouty arthritis outbreak following surgery

Colchicine (Colcrys)

• to increase tear production in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca

Cyclosporine Emulsion (Restasis)

• HTN

• angina pectoris

Atenolol (Tenmorin)

• essential HTN when used alone or in combination with other antihypertensive agents, especially thiazide-type diuretics

• mild to moderate HF of ischemic or cardiomyopathic origin, in combination with digitalis, diuretics, and an ACE inhibitor, to reduce the progression of disease

• for use in patients with left ventricular dysfunction following MI

Carvedilol (Coreg & Coreg CR)

• HTN

• angina pectoris (long-term)

• stable, symptomatic HF of ischemic, hypertensive, or cardiomyopathic origin

Metoprolol Succinate (Toprol-XL & Kapspargo)