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Two reasons why we care about the musculoskeletal system
Provide guidelines for design; minimize cost of injuries
Two functions of connective tissues
Force transmission and movement; metabolism (blood cell manufacture)
Two fiber types associated with connective tissues
Collagen and elastin
Collagen â effect on mechanical properties
Prevent connective tissues from tearing and stretching too easily when subjected to high loads
Elastin â effect on mechanical properties
Once the stretching force is removed, they allow the tissue to snap back to its original shape and resting length
Tendon
Connects muscle to bone; allows body to move joints and maintain posture
Ligament
Connects bone to bone; holds articulating bones in proper alignment and limits abnormal ranges of motion (preventing dislocations)
Stress-strain curve: Y-axis
Stress (force/unit area that results from an applied load-tension), within the tissue
Stress-strain curve: X-axis
Strain (physical deformation response of a material)
Elastic region: Linear & Elastic Phase
Stress is directly proportional to strain; if the applied load is removed anywhere in this region, the tissue completely returns to its original size and shape
Elastic region: Limits of Proportionality
The point where the curve bends slightly; the tissue remains elastic, but the linear relationship between stress and strain ends
Elastic region: Yield Strength
The critical threshold marking the boundary between temporary elastic behavior and permanent structural change
Plastic region: Permanent Deformation
Tissue is permanently altered by stress and cannot fully recover
Stress-strain curve: Point B
Unloading
Stress-strain curve: Point A
The maximum stress level the tissue can withstand before structural breakdown accelerates
Stress-strain curve: Fracture Point
The final point on the curve where the tissue undergoes structural failure, tearing or rupturing completely
Wolff's Law
Bone is deposited where needed and reabsorbed where not needed, based on the mechanical stresses on it
How age affects bone density
Gradual loss of minerals and structural growth
One function of joints
Hold bones together, giving stability, but also gives skeleton mobility
Three types of joints
Synovial, cartilaginous, fibrous
Synovial joint â example location
Elbow
Cartilaginous joint â example location
intervertabrae disc
Fibrous joint â example location
Skull
Three types of cartilage
Hyaline cartilage, fibrocartilage, elastic cartilage
Hyaline cartilage â location
On bones, articular surfaces
Fibrocartilage â location
On disc, intervertebral discs
Elastic cartilage â location
Ear and nose
Why it is difficult to recover from cartilage injuries
Because cartilage lacks a direct blood supply
Two variables that affect spine compressive strength
Age and gender
Three factors that increase the risk of joint injury
Aging, inflammation, previous injuries
Two functions of muscles
Skeletal motion and skeletal stability
Three types of muscles
Skeletal, cardiac, smooth
Skeletal muscle â example
Bicep
Cardiac muscle â example
Walls of heart
Smooth muscle â example
Stomach
How muscles are organized
Organized in agonist-antagonist pairs
Agonist
Muscle causing movement
Antagonist
Muscle opposing agonist
How muscles contract
From the binding/unbinding of two protein molecules: actin and myosin
Two important mechanical properties of muscles
Length-tension relationship and velocity-tension relationship
Length-tension relationship
Describes hohow much force a muscle can produce depends on its length before it contracts
Sliding Filament Theory
The foundational mechanism explaining how muscles contract at a cellular level
When peak muscle force occurs
Peak muscle force (strength) depends on muscle length (posture) and occurs at the optimal resting length
Velocity-tension relationship
how much force a muscle can produce depends on how fast itâs moving. The faster it shortens, the less force it can produce
Two muscle fiber types
Slow (type I) twitch fibers and fast (type II) twitch fibers
Slow (type I) twitch fibers
Fatigue resistant, low force
Fast (type II) twitch fibers
Quick to fatigue, high force
Rohmert curve
Relationship of static endurance time vs. percent of max muscle force; more effort a static hold takes, the faster endurance drops
Rohmert curve â implication on design
Minimize static postures and holds; use mechanical aids and fixtures; keep exertions below the 15% threshold
Two effects aging has on muscles
Loss of muscle mass; general decrease in muscle capacity/strength

Name 1-3 and 7
articular cartilage, joint capsule, synovial fluid, synovial membrane