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Connective Tissue Functions
-surrounds organs and cavities
-connect tissues
-sometimes used to store things
-transportation
-connect adjacent anatomical structure
-help facilitate movement
-padding, cushion, insulation
-protection
blasts
create the matrix
clasts
break the matrix down for remodeling
cytes
maintain the matrix
adipose/fat cells (adipocytes)
common in some tissue (dermis of skin), rare in some (cartilage); store energy
mast cells
common beneath membranes and along small blood vessels
-important role in inflammation and release heparin (blood clots)
white blood cells (leukocytes)
respond to injury or infection
macrophages
phagocytizr foreign and injured cells; protect against infection
fixed macrophages
stay in position in connective tissue
wandering macrophages
move by amoeboid movement through the CT
platelets
fragments of hematopoietic cells involved in blood clotting
undifferentiated mesenchymal cells
type of adult stem cells with potential to differentiate into multiple cell types
collagen (protein)
most common protein in matrix, lot of tensile stength, flexible, relatively inelastic
reticular fibers (protein)
fill space between tissues and organs (forms branching networks)
elastic fibers (protein)
recoiled fibers
Ground substance
gel-like mixture of non-fibrous molecules lubricated/slippery, attract and hold water
proteoglycan
a protein with long polysaccharides (love water)
glycosaminoglycans
pieces that makeup proteoglycans (love water)
mesoderm
1 out of 3 primary embryonic germ layers
mesenchyme
loosely organized embryonic tissue containing undifferentiated cells
specialized connective tissue
ECM changes dramatically as connective tissues specialize
areolar tissue (CT proper - loose)
features: fine network of collagen, lots of space/cushion. contains fibroblasts & macrophages
location: epithelial basement membrane, superficial dermis
adipose tissue (CT proper - loose)
features: large, clear adipocytes (fat cells) w/ peripheral nuclei. functions for insulation, energy storage, and protection
location: dermis, mammary glands
reticular tissue (CT proper - loose)
features: delicate net-like mesh that holds fluids & suspends free-floating cells (leukocytes)
location: lymph nodes, spleen, bone marrow
Dense regular Collagenous (CT proper - Dense)
function: tightly packed parallel fibers. Great parallel tensile strength, poor perpendicular strength.
Location: tendons, ligaments
Dense Irregular collagenous (CT proper - Dense)
Function: fibers point in every direction, high tensile strength from all directions
location: dermis of the skin
Dense regular elastic (CT proper - Dense)
function: parallel alignment, but recoils and stretches
location: vocal cords, ligaments of vertebrae
Dense irregular elastic (CT proper - Dense)
Function: multi-directional recoil and stretch
location: walls of arteries
Cartilage
composed of chondrocytes within lucunae
avascular and aneural (heals very slowly via diffusion)
rich in proteoglycans for rebounding
hyaline cartilage
features: small, evenly dispersed collagen. Rigid but flexible allows long bone growth.
location: ribs, nose, trachea, knee joint
fibrocartilage
features: thick collagen bundles. withstands immense pressure
location: intervertebral discs, meniscus, labrum
elastic cartilage
features: elastic fibers in matrix. provides shape, rigidity, and high flexibility
location: ear pipe
bone
hard connective tissue composed of osteocytes and a solid, mineralized matrix
spongy (Trabecular) bone
features: contains bone trabecular and lots of space filled w/ bone marrow strong but lightweight
location: interior of long bones
compact (cortical) bone
features: densely packed, hard, and heavy. Matrix organized into concentric lamellae surrounding central canals w/ osteocytes in lacunae, massive support
location: outside covering of bone
blood (fluid transport)
matrix: fluid plasma
function: transports oxygen + waste, regulates temp.
cells: RBC, WBC (leukocytes), platelets
Bone marrow (hematopoietic tissue)
locaiton: lives inside the spongy cavities of bone
red marrow: produce blood cells (hematopoiesis)
yellow marrow: stores fat (adipocytes)
Mucous membranes
lines cavities open to the outside (respiratory, digestive)
contain goblet cells that produce mucus
serous membrane
line closed cavities not open to the exterior. secret lubricating serous tissue
synovial membrane
found at the ends of bones. forming joints. create synovial fluid rich in hyaluronic acid