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Pyelonephritis
inflammation of the renal pelvis and the kidney
Chronic Pyelonephritis
Interstitial fibrosis and atrophy of tubules due to multiple bouts of acute pyelonephritis
Can be associated with chronic UTI's, vesicoureteral reflux, or kidney stones
Cystitis
Inflammation of the bladder
Common pathogens are E. Coli and staphylococcus saphrophyticus
Symptoms of cystitis
Frequency, urgency, dysuria, lower back pain
Renal cell carcinoma
cancerous tumor that arises from kidney tubule cells
Renal adenoma
small, slow-growing glandular noncancerous tumor of the kidney
Renal transitional cell carcinoma
rare and primarily arises in the renal parenchyma and renal pelvis.
Transitional cell carcinoma
a malignant tumor of the urinary tract that is often found within the urinary bladder or within the renal pelvis. Generally occurs in older men. Gross painless hematuria
Gomerulonephritis
inflammation of the glomeruli within the kidney
Primary glomerulonephritis
inflammation of the glomeruli of the kidneys that occurs independently of other chronic conditions; usually the result of an acute infectious process
secondary glomerulonephritis
inflammation of the glomeruli of the kidneys that results from other chronic conditions, such as lupus erythematosus or diabetes.
Symptoms of glomerulonephritis
Hematuria with red blood cell casts, proteinuria with albumin, oliguria, HTN, edema, nephrotic sediment
Types of glomerulonephritis
- membranous nephropathy/ glomerulonephritis
- rapidly progressing glomerulonephritis
-Anti-glomerular basement membrane disease (goodpasture syndrome)
- chronic glomerulonephritis
-diabetic neuropathy
Nephrotic syndrome
loss of large amounts of plasma protein, usually albumin, through urine due to an increased permeability of the glomerular membrane
Causes of nephrotic syndrome
Membranous glomerulonephritis
Minimal change nephropathy
Focal segmental glomerulosclerosis
-systemic disease such as diabetes or lupus
Hypospadias
congenital abnormality in which the male urethral opening is on the undersurface of the penis, instead of at its tip
Epispadias
Opening of the urethra on the superior surface of the penis
Chordee
a downward curvature of the penis, often associated with hypospadias
Nephroblastoma (Wilms tumor)
A rapidly developing malignancy of the kidneys, usually affecting children before age 5. Normally found by parents due to swelling.
PCOS diagnosis
Have to have two of the following:
-Irregular ovulation
-Elevated levels of androgen
-Polycystic ovaries on ultrasound
PCOS (polycystic ovarian syndrome)
An endocrine disorder associated with chronic anovulation, most common in young women (teens to twenties). High LH/FSH ratio in blood; A hormonal disorder causing enlarged ovaries with small cysts on the outer edges.
Chlamydia
A bacterial infection that affects the reproductive organs of both males and females. Can cause permanent damage to a woman's reproductive system. Can also cause ectopic pregnancy.
Symptoms of Chlamydia
urethritis; penile and vaginal discharges; abdominal, rectal, or testicular pain; painful intercourse; irregular menses
Syphilis
an STD that attacks many parts of the body and is caused by a small bacterium called a spirochete. 3 phases
Primary stage of syphilis
the first few weeks of a syphilis infection during which the chancre is present and can be present on the mouth, penis, vagina, anus
secondary stage of syphilis
Skin rashes and/or sores in the mouth, vagina, or anus. A rash that appears on the soles of the feet or palms. Fever, swollen lymph nodes, sore throat, patchy hair loss, headaches, weight loss, muscle aches, fatigue
Latent syphilis
the third stage of syphilis, which may last for years, during which symptoms disappear although the person is still infected
Tertiary syphilis
Damages internal organs and can result in death if not treated
Ghonnorea
Infects the mucus membrane of the reproductive tract including the cervix, uterus, and fallopian tubes in women. The urethra can be affected in women and men
Ghonnorea symptoms
Discharge, dysuria, unusual sores, or rash
Trichomoniasis
an STD caused by a microscopic protozoan that results in infections of the vagina, urethra, and bladder
Trichomoniasis symptoms
Itching, burning, redness, sores, dysuria, clear, white yellow, or green vaginal discharge with a fishy smell
Vaginal candidiasis
a vaginal infection caused by the yeast-like fungus Candida albicans; also known as a yeast infection.
Vaginal Candidiasis symptoms
Itching, soreness, dyspareunia, dysuria, abnormal vaginal discharge (thick, white)
Bacterial vaginosis
An overgrowth of bacteria in the vagina; characterized by itching, burning, or pain, and possibly a "fishy" smelling discharge.
Ovarian cysts
collections of fluid within a sac (cyst) in the ovary
Follicular cysts
transient condition in which the dominant follicle fails to rupture
corpus leutum cyst
Highly vascularized cysts formed by the granulosa cells left behind after ovulation
Can rupture and cause hemorrhage
Dermoid cyst
ovarian teratomas that contain elements of all three germ layers. Have malignant potential
Cervical cancer
Malignant cell growth in the cervix; can be caused by HPV virus. Normal cervical cells change to dysplasia to carcinoma in situ and eventually invasive cancer. Predominantly asymptomatic
Vulvar cancer
-Usually squamous cell carcinoma
-Associated with HPV, increasing age, previous cancer, autoimmune conditions, and immunosuppression
Endometrial cancer
malignant tumor of the endometrium (also called uterine cancer). Primary risk factor is unopposed estrogen exposure (without progesterone). Manifested by abnormal vaginal bleeding.
Ovarian cancer
malignant tumor of the ovary. Usually no early symptoms
Paraphimosis
condition in which a retracted foreskin cannot be pulled forward to cover the glans
Phimosis
Inability to retract foreskin. Frequently caused by poor hygiene
Peyronie's disease
"Bent nail syndrome". Slow development of fibrous plaques in the erectile tissue of the corpus cavernosa, causing lateral curvature of the penis during erection
Priapism
Prolonged erection. Urologic emergency. Have to drain blood from the penis.
Balantitis
Inflammation of the glans penis. Accumulation under the foreskin can irritate the glans and lead to infection.
Category 1 prostatitis
-acute bacterial prostatitis
-Ascending infection of the urinary tract
-infection stimulates an inflammatory response in which the prostate becomes enlarged, tender, firm, or boggy
Category 2 prostatitis
chronic bacterial prostatitis. Recurrent urinary tract symptoms and persistence of pathogenic bacteria in urine or prostatic fluid. Prostate may be fibrotic from frequent infection.
Category 3 prostatitis
chronic prostatitis/chronic pelvic pain. No pathogenic bacteria can be localized to the prostate.
-category 3a- chronic pelvic pain syndrome with WBC count elevated and localized to prostate
-category 3b- noninflammatory
Category 4 prostatitis
Asymptomatic inflammatory prostatitis. There is an increase in bacteria and WBC localized to the prostate.
GERD
Reflux of gastric contents into the esophagus
GERD symptoms
-Heartburn 30-60 minutes after meals with reclining
-Relief with antacids
-Regurgitation/reflux
-Dysphagia
-Asthma
-Cough
-Laryngitis
-Sore throat
-Chest pain
Hiatal hernia
A condition in which a portion of the stomach protrudes upward into the chest, through an opening in the diaphragm.
Peptic Ulcer Disease
A break or ulceration in the protective mucosal lining of the lower esophagus, stomach, or duodenum.
-superficial: Erosions
Duodenal ulcers
Ulcers of the small intestine caused by NSAIDs and Helicobacter pylori infection. Characterized by intermittent pain in the epigastric area
-relieved rapidly by ingestion of foods or antacids
Ulcerative colitis
a chronic condition of unknown cause in which repeated episodes of inflammation in the rectum and large intestine cause ulcers and irritation.
Symptoms of ulcerative colitis
hematochezia, diarrhea with mucus/pus, tenesmus, rectal urgency
Chron's disease
A chronic inflammatory bowel disease that affects the lining of the digestive tract. Skip lesions. Ulcerations that can cause fissures that extend into the lymphatics. Anemia may result from the malabsorption of B vitamins and folic acid.
Celiac disease
Gluten causes inflammation in the small intestine which leads to malabsorption and decreased functionality. Bloating, chronic diarrhea, constipation, gas, loose stools, nausea, vomiting, abdominal pain
Pancreatitis
Inflammation of the pancreas. Develops due to an obstruction of the outflow of pancreatic enzymes caused by bile and pancreatic duct obstruction
Acute pancreatitis
May result from drugs, cellular injury from alcohol, or viral infection
-epigastric or midabdominal constant pain
Chronic pancreatitis
Process of progressive fibrotic destruction of the pancreas
Related to chronic alcohol abuse
Continuous or intermittent abdominal pain and weight loss are common
Risk factor for pancreatic cancer
Cirrhosis
irreversible, chronic, progressive degeneration of liver w/fibrosis. s/s: fatigue, hepatomegaly, RUQ pain, jaundice, steatorrhea, clay-colored stools, ascities, hepatic encephalopathy. Rx: steroids, vit B.
Alcoholic liver disease
A degenerative liver condition that occurs in three stages: (1) fatty liver, (2) alcoholic hepatitis, and (3) cirrhosis.
Portal hypertension
Elevation of blood pressure within the portal venous system.
Esophageal varices
Enlarged and swollen veins at the lower end of the esophagus caused by portal hypertension. Rupture leads to hemorrhage. Vomiting leads to large amounts of blood, black or tarry stools, lightheadedness, loss of consciousness
Hepatic encephalopathy
Cells in the nervous system are vulnerable to neurotoxins absorbed by the GI tract that, because of liver dysfunction, circulate to the brain. s/s: change in LOC, memory loss, asterixis (flapping tremor) impaired handwriting, hyperventilation w/ resp alkalosis. Rx: lactulose, low protein, safety, rest
Biliary atresia
Congenital absence of the opening from the common bile duct into small intestine (duodenum). Plugging, inflammation, and fibrosis of the bile ducts and cholestasis. Jaundice is the primary symptom. Liver-transplant for long-term therapy.
Pyloric stenosis
Narrowing of the opening of the stomach to the duodenum. Forceful and nonbilious vomiting immediately after feeding. Vomiting causes weight loss, electrolyte imbalance, and dehydration. Hypertonic pylorus is palpable in RUQ.
Intussusception
Telescoping of a segment of the intestine into a distal segment, causing an obstruction. Causes bleeding, necrosis, and bowel perforation, if not treated. Abdominal pain, irritability, vomiting, and "current jelly-like stools". Reduction with enema and possible correction with surgery.
Diverticula
A sac-like outpouching of the wall of the small intestine that is present in some children at birth. Painless rectal bleeding or the diverticulum becomes infected.