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Ferrous fumarate elemental iron content
107mg
Ferrous sulfate elemental iron content
65mg
Ferrous gluconate elemental iron content
39mg
Iron products dosing frequency
Daily or once every other day
What increases iron absorption?
Empty stomach
Vitamin C — controversial
What metals decrease iron absorption?
Calcium, magnesium, aluminum — look out for antacids
What drugs decrease iron absorption?
PPIs (e.g. omeprazole), H2RAs (e.g. famotidine)
Main foods that decrease iron absorption
Coffee, tea, cereal, dairy
Oral iron administration in relation to interacting drugs
Administer iron product 2 hours before H2RAs or PPIs
IDA length of therapy
3 months; may need lifelong if cause cannot be removed
Main ADRs to iron products
Stomach irritation
Dark stools — harmless
Constipation
Nausea
Keep iron away from…
children — toxic!!!
What to use if oral iron does not work or cannot be given due to contraindication
IV iron
Contraindications to oral therapy
Decrease absorption:
Celiac disease
Bariatric surgery