Endocrine Disorders

Hyperthyroidism

• Grave’s Disease

• Excessive iodine

Cushing’s Syndrome

Excessive glucocorticoid secretion (cortisol)

Addison’s Disease

Decrease in ALL adrenal cortex hormones

Hyperaldosteronism

• Conn’s Syndrome

• Increased aldosterone secretion from benign adrenal cortex tumor

Metabolic Syndrome

Risk factors:

• High glucose

• High BP

• High triglycerides

• Low HDL

• Increased waist circumference

Hypoparathyroidism

• Decreases PTH = Decreased serum calcium

• Diarrhea, anxiety, hypotension

Hypopituitarism

• Dwarfism

• Diabetes Insipidus

Thyroid Crisis/Thyroid Storm

• Sudden worsening of hyperthyroidism symptoms

• May occur with infection, stress, or removal of thyroid gland

Type 2 Diabetes

• Primarily affects adults

• Decreased insulin production or defect in insulin itself

Hyperparathyroidism

• Increased PTH = Increased serum calcium

• Renal calculi, constipation, depression

Pheochromocytoma

• Rare tumor in adrenal medulla

Hyperpituitarism

• Usually caused by tumor

• Gigantism, Acromegaly, SIADH

Hypothyroidism

• Hashimoto’s (autoimmune thyroiditis)

• Increased TSH, decreased T3 / T4

Gestational diabetes

• Onset during pregnancy

• Increased risk of developing Type 2 Diabetes

Myxedema

• Hypothyroid crisis, advanced hypothyroidism

• Triggered by illness, infection, trauma, exposure to cold

Type I Diabetes

• Primarily affects children

• Autoimmune; beta cells destroyed

• No insulin