LESSON 11

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These flashcards cover key vocabulary and concepts related to molecular systematics, emphasizing definitions and essential terms from the lecture notes.

Last updated 2:49 PM on 12/10/25
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27 Terms

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Molecular Systematics

A field that uses molecular data to analyze and reconstruct evolutionary relationships between organisms.

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Phylogenetic Tree

A diagram that represents evolutionary relationships among biological species based on similarities and differences in their physical or genetic characteristics.

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DNA Sequencing

The process of determining the exact sequence of nucleotides within a DNA molecule.

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Homologous Genes

Genes in different species that evolved from a common ancestor and usually retain similar sequences.

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Mutation

A change in the nucleotide sequence of an organism's DNA, which can lead to variations in traits.

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Substitution Mutation

A type of mutation where one base pair in the DNA sequence is replaced by another.

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Indel Mutations

Insertions or deletions of nucleotides in a DNA sequence; these can complicate sequence alignment.

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Genetic Distance

A measure of the genetic divergence between species; expressed as the number of nucleotide differences per site.

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Maximum Likelihood

A statistical approach for inferring phylogenies that selects the tree topology with the highest probability of producing the observed data.

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Bayesian Inference

A method of estimating phylogenies that incorporates prior probabilities with observed data to infer tree solutions.

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Parsimony Method

A tree-building method that prefers the simplest explanation or the tree with the least number of changes.

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Mitochondrial DNA

DNA located in the mitochondria that is inherited maternally and is useful in evolutionary studies.

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Genome

The complete set of genes or genetic material present in a cell or organism.

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Sequence Alignment

A method of arranging the sequences of DNA, RNA, or protein to identify regions of similarity.

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Nucleotide Position

The specific location of a nucleotide within a DNA or RNA sequence.

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Positional Homology

The correspondence of nucleotide positions between sequences that can trace back to a common ancestor.

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Insertion

A mutation where one or more nucleotides are added to a DNA sequence.

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Deletion

A mutation where one or more nucleotides are removed from a DNA sequence.

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Clade

A group of organisms believed to have evolved from a common ancestor.

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Informative Sites

Nucleotide positions in a sequence that provide significant phylogenetic information.

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Autapomorphies

Derived characteristics that are unique to a particular lineage.

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UPGMA

Unweighted Pair Group Method with Arithmetic Mean; a method used for constructing phylogenetic trees.

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Gene Tree

A tree that represents the evolutionary relationships of a particular gene across different species.

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Species Tree

A phylogenetic tree that illustrates the evolutionary relationships among different species.

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Clock Model

A model that describes the rate of evolution for sequences in a phylogenetic analysis.

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Markov Chain Monte Carlo (MCMC)

A computational method used for estimating complex probabilities and exploring possibilities in phylogenetic analysis.

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Frontal Alignment

The alignment of nucleotide sequences that provides insights into their evolutionary relationships.