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An age related eye disease that affects central vision
What is macular degeneration?
A condition where the cornea bulges into a cone shape
What is keratoconus?
Blindness due to progressive diseases involving an increase in eye pressure
What is glaucoma?
An inherited condition that causes the cells in your retina to gradually stop working
What is retinitis pigmentosa?
The macula at the back of the eye begins to waste away
Mechanism for macular degeneration
Weakening of corneal structure and breakdown of collagen lead to increased intraocular pressure and bulging of cornea into cone shape
Mechanism for keratoconus
Aqueous humor built up in the eye causes pressure, damaging the optic nerve
Mechanism for glaucoma
Photoreceptors gradually start to fail, so images sent to the brain become unable to be interpreted
Mechanism for retinitis pigmentosa
blurred vision, dark spot infield of vision, lines appear distorted
Symptoms of macular degeneration
Distorted vision, halos around bright lights, double vision in one eye
Symptoms of keratoconus
blurred vision, eventual loss of side vision, blind spots in peripheral vision
symptoms of glaucoma
night blindness, bright light sensitivity, tunnel vision
symptoms of retinitis pigmentosa
high intraocular pressure, family history, long use of corticosteroids
risk factors for glaucoma
smoking, obesity, eye trauma
risk factors for retinitis pigmentosa
osteogenesis imperfecta, down syndrome, congenital eye disorder (anirida)
risk factors for keratoconus
smoking, obesity, hypertension, family history
risk factors for macular degeneration
photodynamic therapy (wet), laser photocoagulation (wet), anti-vascular endothelial growth factor injections (anti-VEGF)
treatments for macular degeneration
glasses/contacts, cornea transplant surgery, corneal collagen cross-linking
treatments for keratonconus
ocular hypertension medicine, beta blockers, and laser therapy
treatments for glaucoma
retinal prosthesis, vitamin A supplements, gene therapy
treatments for retinitis pigmentosa
perimetrium, connective tissue (pelvic wall)
What is the outermost layer of the uterus and what is it’s tissue?
myometrium, which is a smooth muscle used for contractions during labor
what in the middle layer of the uterus and what is its function?
Endometrium, composed of stratum basal and stratum functionale, acts as the site for implantation of zygote.
what is the innermost layer of the uterus, what is it made of and what does it do?
the stratum basale replaces the stratum functionale when it sheds each month during menstruation.
what is the relationship between stratum basale and stratum functionale?
retina, choroid, and sclera
what are the layers of the eye?
replaced constantly in the anterior cavity, it is important for eye nourishment, intraocular pressure, and is produced by the ciliary body
what is aqueous humor, what cavity is it in, and how often is it replaced?
we are born with it, so there is no replacement, it’s located in the posterior cavity, and it is a gel-like liquid that holds the retina in place
what is vitreous humor, what cavity is it in, and how often is it replaced?
the cornea
what part of the eye is responsible for 2/3 of refraction?
the lens
what part of the eye is responsible for 1/3 of refraction and accommodation?
regulates the lens thickness
what does the ciliary muscle do?
lubrication and protection
what is the conjunctiva responsible for?
this is where blood vessels and the optic nerve exit the eye - no photoreceptors are present
what is the purpose of the optic disk?
mostly cones and some rods
the macula lutea contains…
the site with the greatest visual acuity and high cone concentration
the fovea centralis is the site with what and contains mainly what?
loss of lens elasticity with age leading to a harder time accommodating with near vision
what is presbyopia?
ciliary muscles = relaxed, zonular fibers = tight, lens = flat
accommodation for FAR (what is happening to ciliary muscles, zonular fibers, and lens?)
ciliary muscles = contracted, zonular fibers = loose, lens = round and thick
accommodation for NEAR (what is happening to ciliary muscles, zonular fibers, and lens?)
emmetropia
what is normal vision called?
rays of light scattered throughout the eye caused by irregular curvature of the cornea or lens
what is astigmatism?
the focus point is behind the retina
where is the focus point in hyperopia?
myopia, diverging lens, concave lens, nearsighted
what does “my diving cave is near” stand for?
focus point is in front of retina
where is the focus point for myopia?
the eye being too long or the lens being too thin
what is myopia caused by?
eye is too short or lens is too thick
what is hyperopia caused by?
ingersoll model
what represents how eyes refract light?
decreases acuity
an increase in convergence in ganglion cells does what to acuity?
photoreceptors, horizontal cells, bipolar cells, amacrine cells, ganglion cells, out to optic nerve (cranial nerve 2)
visual pathway: PhBaG
no M cone (green) so green is seen as red
what is deuteranopia?
no L cone (red), so red is seen as green
what is protanopia?
lacks all cones, so it’s black and white vision
what type of colorblindness is achromatopsia?
an extra cone results in increased visual acuity
what is tetrachromacy?
red
L cone (562 nm)
green
M cone (530 nm)
blue
S cone (420 nm)
thins uterine lining, preventing implantation
what does progestin do?
causes no LH surge, resulting in no ovulation
what does moderate estrogen do for birth control?
follicular phase and luteal phase
the ovarian cycle consists of what two phases?
menstruation, proliferative phase, secretory phase
the uterine cycle consists of what three phases?
follicular phase
what phase in the ovarian cycle occurs before ovulation?
five to six weeks
reproductive structures are identical in male and female embryos until ___________ weeks
testosterone, eight
leydig cells begin releasing __________ at _________ weeks
Mullerian-inhibiting factor (MIF)
what do sertoli cells secrete?
urogenital sinus, labioscrotal swelling, genital tubercle, and urethral folds
both genders have what four things?
testosterone is converted to dihydroxytestosterone (DHT) by 5 alpha-reductase
what is masculinization?