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What is the purpose of fatty acid synthesis?
Build fatty acids from acetyl CoA when nutrients are abundant
Where does fatty acid synthesis take place?
Cytosol
What is the rate-limiting enzyme for fatty acid synthesis?
Acetyl CoA-carboyxlase (ACC)
What must occur before the steps of fatty acid synthesis?
ACC must convert acetyl CoA into malonyl CoA
What is the first step of fatty acid synthesis?
Attach
Acetyl and malonyl groups are attached
What is the second step of fatty acid synthesis?
Condense
Acetyl and malonyl groups combine releasing CO2 and extending fatty acid chain
What is the third step of fatty acid synthesis?
Reduce
NADPH supplied electrons to turn carbonyl into hydroxyl group
What is the fourth step of fatty acid synthesis?
Dehydration
Water is removed to create a carbon carbon double bond
What is the fifth step of fatty acid synthesis?
Reduce
NADPH reduces carbon carbon double bond to create saturate fatty acid