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eidos
The Platonic concept of fixed, idealized forms that dominated pre-Darwinian Western thought.
besoin
Lamarck’s concept of physical "needs" created by environmental shifts that stimulate the acquisition of traits.
plenitude
The assumption that a perfect creator would leave no gaps in nature and permit no extinctions.
catastrophism / uniformitarianism
Early geological frameworks; catastrophism relied on sudden events to explain fossils, while Hutton's uniformitarianism provided a framework for slow, continuous planetary change.
Scala Naturae
The Great Chain of Being linking inanimate matter through plants and animals to angels/God.
Essentialism
The belief that intra-species variations are merely imperfect copies of an ideal form.
Homology vs. Analogy
Homology is similarity due to descent from a common ancestor; Analogy is similarity despite different ancestry, driven by convergent evolution.
Cladogenesis
The splitting of evolutionary lineages where independent mutations accumulate.
Synapomorphies
Shared, derived traits used to map evolutionary relationships.
Parsimony
The principle that the most accurate phylogenetic tree requires the fewest total evolutionary changes or steps.
Molecular clock
Using genetic divergence (percent nucleotide differences) to track evolutionary time.
Exaptations
Traits that originally evolved for one function but were later co-opted for another (e.g., dinosaur feathers for flight).
Monophyletic / Paraphyletic / Polyphyletic groups
Monophyletic
A true clade containing an ancestor and all its descendants.
Paraphyletic
Excludes some descendants (e.g., Reptilia excluding birds).
Polyphyletic
Groups organisms without an exclusive recent common ancestor (e.g., "warm-blooded vertebrates").
Synonymous (silent) vs. Non-synonymous mutations
A 3rd position codon mutation is mathematically 69% likely to be synonymous (invisible to selection); a 2nd position mutation is 100% likely to be non-synonymous (alters the amino acid).
Central Dogma
The unidirectional flow of information
Germline vs. Soma
Weismann’s doctrine separating reproductive cells (germline) from body cells (soma), proving somatic mutations cannot be inherited.
Transitions vs. Transversions
Transitions are purine-to-purine or pyrimidine-to-pyrimidine swaps; Transversions are cross-category purine-to-pyrimidine swaps.
Single Nucleotide Polymorphisms (SNPs) & Haplotypes
SNPs are single variable nucleotides (~1 every 1000 bp in humans); a haplotype is a set of linked SNPs along a single chromosome.
Pleiotropy vs. Epistasis
Pleiotropy is one mutation causing multiple phenotypic effects; Epistasis is the expression of one locus being modified by the genotype of a separate interacting locus.
Canalized vs. Plastic
Genotypes with no response to environmental changes are canalized; sensitive genotypes are plastic.
Genotype-by-Environment (GxE) interaction
When different genotypes respond to the same environmental shift in fundamentally different, non-parallel ways.
Directional / Stabilizing / Disruptive Selection
Directional
Favors phenotypic extremes.
Stabilizing
Favors intermediates.
Disruptive
Favors both extremes over intermediates.
Overdominance (Heterosis)
Balancing selection where heterozygotes exhibit fitness superior to either homozygote.
Marginal Overdominance
A mathematical state where the heterozygote may not be the fittest in any single niche, but its weighted average fitness across all available niches outperforms both homozygotes.
Multiple Niche Polymorphism
Different habitats favoring different genotypes across a landscape.
Linkage disequilibrium (D)
The non-random association of linked alleles.
Coupling gametes (AB, ab)
push D toward 0.25.
Repulsion gametes (Ab, aB)
push D toward -0.25.
Genetic hitchhiking
Neutral/deleterious variants physically linked to a favored variant are dragged to high frequency during a selective sweep.
Supergenes
Tightly linked clusters of interacting loci with highly favorable allelic combinations that behave as a single genetic unit due to suppressed recombination.
Founder Effect
A specific subset of genetic drift where sampling error occurs upon the geographic establishment of a new, tiny population.
Natural Selection
The true driving force of evolution identified by Darwin and Wallace, where heritable intra-species variation results in differential survivorship and reproductive success.
The Modern Synthesis
Developed in the 1920s by R.A. Fisher, Sewall Wright, and J.B.S. Haldane to unite Darwinian selection with particulate Mendelian factors, solving the fatal mathematical flaw of "blending inheritance."
The Law of Succession
Extant organisms strongly resemble extinct fossil forms found in the identical geographic region.
The Classical vs. Balance Debate (Neutralist-Selectionist)
Classical School (H.J. Muller)
Populations harbor low variation because purifying selection aggressively eliminates mutants to favor a "wild type."
Balance School (T. Dobzhansky)
High variation is actively maintained via balancing selection and heterozygote advantage.