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what can cellular membranes be equated to?
fluid mosaics of lipids and proteins
phospholipids are amphipathic molecules, meaning they contain what regions?
hydrophobic and hydrophilic regions
the hydrophilic tails of phospholipids are in what part of the membrane?
they are inside the membrane
the hydrophilic heads of phospholipids are exposed to what?
water on either side
the phospholipid membrane is a mosaic of what type of molecules?
protein molecules
membranes must be what to work properly?
fluid
membranes that have more unsaturated fatty acids are more…
fluid than those rich in saturated fatty acids
cholesterol has _____ affects on the membrane fluidity of animal cells
different
at warmer temperatures, what does cholesterol do to the movement of phospholipids?
restrains the movement
what are peripheral proteins?
they are bound to the surface of the membrane
what are integral proteins?
they penetrate the hydrophobic core
if integral proteins span the entire membrane what are they called?
a transmembrane protein
what do the hydrophobic regions of an integral protein consist of?
one or more stretches of non-polar amino acids, often coiled into alpha helixes
cell-surface membranes can carry out several functions, such as
transport, enzymatic activity, signal transduction, cell-cell recognition, intercellular joining, attachment to the cytoskeleton and extracellular matrix (ECM)
how do cells recognize each other?
they bind to molecules often containing carbohydrates on the extracellular surface of the plasma membrane
cell-cell recognition happens by using
carbohydrates
what does a cell have to do through the membrane?
a cell must exchange materials with its surroundings
what type of molecule can dissolve in the lipid bilayer and pass through the membrane rapidly?
a hydrophobic (non-polar) molecule
What type of molecules cannot just pass straight through the membrane?
hydrophilic molecules
what do proteins built into the membrane do?
they play key roles in regulating transport
transport proteins allow the passage of what type of substances across the membrane and are specific for the molecules they move?
hydrophilic substances
what is passive transport?
diffusion of a substance across a membrane with no energy investment
diffusion is
the tendency for molecules to spread out evenly into the space available
which way do substances diffuse?
down the concentration gradient
what is the concentration gradient?
the region along which the density of a chemical substance increases or decreases
diffusion takes what type of work?
no work
why is diffusion passive transport?
because it expends no energy for the cell to make it happen
osmosis is
the diffusion of water across a selectively permeable membrane
which way does water diffuse in osmosis?
across a membrane from a region of lower solute concentration to a region of higher solute concentration
what is tonicity?
the ability of surrounding solution to cause a cell to gain or lose water
what is an isotonic solution?
solute concentration is the same as the inside of the cell, there is no net water movement across the plasma membrane
what is a hypertonic solution?
solute concentration is greater than that inside the cell, the cell loses water
what is a hypotonic solution?
solute concentration is less than that inside the cell, the cell gains water
what is osmoregulation?
the control of the solute concentrations and water balance
what happens to cells without cell walls in hypertonic and hypotonic solutions during osmoregulation?
they will shrivel in a hypertonic solution and burst (lyse) in a hypotonic solution
what is facilitated diffusion?
transport proteins speed the passive movement of molecules across the plasma membrane
what is the purpose of a channel protein?
they provide corridors that allow a specific molecule or ion to cross the membrane
aquaporins facilitate what?
diffusion of water
ion channels facilitate the transport of what?
ions
ion channels are specialized types of what?
aquaporins (smaller)
what do carrier proteins undergo?
a subtle change in shape that translocates the solute-binding site across the membrane
what is the cause of carrier proteins changing shape?
chemical interactions and repulsions; not energy related
changes in shape for carrier proteins occur because of what?
the binding and release of the transported molecules