307 exam 3 book Q

Neutrophils and monocytes are direct descendants of a common progenitor known as:

GMP

The stage in neutrophilic development in which the nucleus is indented in a kidney bean shape and the cytoplasm has secondary granules that are lavender in color is the:

Metamyelocyte

Type II myeloblasts are characterized by:

The presence of fewer than 20 primary granules per cell

Which one of the following is a function of neutrophils?

Protection against reexposure by same antigen

Which of the following cells are important in immune regulation, allergic inflammation, and destruction of tissue invading helminths?

Eosinophils and basophils

Basophils and mast cells have high-affinity surface receptors for which immunoglobulin?

E

Which of the following cell types is capable of differentiating into osteoclasts, macrophages, or dendritic cells?

Monocytes

Macrophages aid in adaptive immunity by:

Degrading antigen and presenting it to lymphocytes

Which of the following is the final stage of B cell maturation after activation by antigen?

Plasma cell

The following is unique to both B and T lymphocytes and occurs during their early development:

Rearrangement of antigen receptor genes

The megakaryocyte progenitor that undergoes endomitosis is:

LD-CFU-Meg

Which of the following inherited leukocyte disorders is caused by a mutation in the lamin B receptor?

Pelger-Huët anomaly

Which of the following inherited leukocyte disorders involves mutations in nonmuscle myosin heavy-chain IIA?

May-Hegglin anomaly

Which of the following inherited leukocyte disorders might be seen in Hurler syndrome?

Alder-Reilly anomaly

Which of the following lysosomal storage diseases is characterized by macrophages with striated cytoplasm and storage of glucocerebroside?

Gaucher disease

The neutrophils in chronic granulomatous disease are incapable of producing:

All of the above

An absolute lymphocytosis with reactive lymphocytes suggests which of the following conditions?

Viral infection

What leukocyte cytoplasmic inclusion is composed of ribosomal RNA?

Döhle bodies

Which of the following is true of an absolute increase in lymphocytes with reactive morphology?

The reactive lymphocytes have increased cytoplasm with variable basophilia.

What is the most common clinical application of flow cytometry?

Diagnosis of leukemias and lymphomas

SBB stains which of the following component of cells?

Lipids

The cytochemical stain α-naphthyl butyrate is a nonspecific esterase stain that shows diffuse positivity in cells of which lineage?

Monocytic