01 CNS Basics

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6 Terms

1
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[CNS] What does the blood-brain barrier do?

Restricts drug entry into brain; lipid-soluble drugs pass more easily.

2
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[CNS] Why are newborns more sensitive to many CNS drugs?

The blood-brain barrier is not fully developed.

3
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[CNS] What are the roles of GABA and glutamate?

GABA inhibits neuronal firing; glutamate is excitatory.

4
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[CNS] What is drug tolerance?

A reduced response after prolonged exposure; higher doses may be needed.

5
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[CNS] What is physical dependence?

Abrupt discontinuation produces withdrawal; not the same as addiction.

6
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[CNS] What is a major nursing priority with sedating medications?

Assess respiratory rate, alertness, fall risk, and other CNS depressants.