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metabolism
the sum of all chemical reaction in a living system
catabolism
the breakdown of complex organic molecules into simpler ones
catabolism generates
energy
anabolism
the use of simple organic molecules ion the biosynthesis f complex ones
anabolsim consumes
energy
metabolism requires the transport of simple and complex ________ into and out of the cell
molecules
requires movement of material across the
cell membrane
the key membrane features
amphipathic
selective permeability
metabolic transport: what can easily pass/what cannot?
small/non polar can eailsy pass
large/charged cannot easily passer
requires _____ proteins
transport
passive transport requires a concentration gradient from
high to low
simple diffusion is movement of compounds from
high to low until equal
diffusion in biological systems usually cannot with
large or charged molecules
osmosis requires a concentration gradient from
high to low
osmosis continues until outside water =
inside water
faciliated diffusion uses membrane _____ to transport molecules and compounds
proteins
facilitated diffusion requires
transporters/permease
facilitated diffusion does not require
ATP or energy sources
facilitated diffusion is a form of what kind of transport
passive transport
nonspecific transporters are most commonly found in
prokaryotes
specific transporters are more common in
prokaryotes
specific transporters allow for the transport of specific
molecules or classes of molecules
example of a non specific transporter
porin protein
example of a specific transporter
glucose transporter
amino acid transporter
active transport does not require a
concentration gradient
active transport moves from
low to high
an enzymes shape determines
substrate specificity/activitey
cofactor
inorganic compound/molecule that aids in enzyme function
co factor can stabilize
charges
co factor an align
substrates
coenzyme is an ______ molecule that
organic
aids in enzyme function
coenzymes often act by donating or accepting
electrons
denaturation
unfolding or misfolding of a protein
denaturation usually results in
inactive enzyme
competitive inhibitors bind to
active site of an enzyme
competitive inhibitors may be structurally similar to
substrates
competitive inhibitors prevent substrate
binding
competitive inhibitors can be
temporary or permanent
noncompetitive inhibitors bind to
locations other than the active side
noncompetitive inhibitors bind to the _____ site
allosteric
noncompetitive inhibitors cause
conformational change that will not allow the substrate to bind
feedback inhibition
when a downstream product acts as a noncompetitive inhibitor
feedback inhibition: too much product
shuts down enzyme activity
oxidative phosphorylation
series of oxidation reduction reactions that result in the formation of ATP
oxidation
loss of electrons
reduction
gaining elections
eukaryotes: oxidation phosphorylation occurs in the
mitochondria
prokaryotes: oxidative phosphorylation occurs in the
cell membrane
glycolysis occurs in the
cell membrane
glycolysis = oxidation of glucose →
2 molecules of pyruvate (pyruciv acid)
glycolysis = limited ATP production
net 2
respiration is
oxidation of a substrate resulting in the reduction of inorganic molecules