Lec13 Acute Lymphoid Leukemias

Which age group is mostly affected with ACUTE LYMPHoid Leukemia?

CHILDREN

Kids typically dont have a chronic leukemia they have ACUTE

Kids also have more LYMPH

Which Acute Lymphoid Leukemia class is MOST COMMON in children?

L1

What is seen in L1 Acute Lymphoid Leukemia?

SMALL LymphoBLASTS

Most seen in children

What is seen in the L2 Acute Lymphoid Leukemia?

LARGER LymphoBLASTS

more common in adults

Which Acute Lymphoid Leukemia is the BURKITT TYPE?

L3 Acute Lymphoid Leukemia

What is seen in the L3 Acute Lymphoid Leukemia?

Large Lymphoblasts with VACUOLES

Which are the IMMUNOlogic types of Acute Lymphoid Leukemia?

REMEMBER Lymphocytes = B cells and T cells

B cell ALL

T cell ALL

CALLa ALL

Null-ALL

What is the LAP score?

This is an indicator of an enzyme in MATURE NEUTROPHILS to indicate how it is reacting

Why would the LAP score DECREASE in Chronic Myeloid Leukemia (CML)?

Remember CHRONIC leukemias have MATURE CELLS, but they are NONFUNCTIONAL

Although we have mature neutrophils, they are NONFUNCTIONAL so their LAP SCORE DECREASES