Steps of Intrammbranous and endochondral ossification

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Last updated 7:27 PM on 10/17/26
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11 Terms

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  1. Intrammbranous


Mesenchymal Tissue- stem cells in connective tissue differentiate into osteoblasts

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  1. Intrammbranous


Osteoid Formation- osteoblasts secrete osteoid

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  1. Intrammbranous


Mineralization- calcium and phosphate crystals are deposited turning osteoid into bone

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  1. Intrammbranous


Osteocytes- some osteoblasts become osteocytes trapped in the matrix

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  1. Intrammbranous


Bone spicules and Trabeculae- trabeculae form and later remodel into lamellar bone

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  1. endochondral


Cartilage mode;- hyaline cartilage model forms

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  1. endochondral


bone collar forms- osteoblasts build a bone collar around the diaphysis

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  1. endochondral


Calcification- cartilage matrix calcifies, causing chondrocytes to die and leaving hollow space

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  1. endochondral


Primary Ossification center- blood vessels invate, bringing osteoprogenitor cells and osteoclasts

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  1. endochondral


secondary ossification center- form in the epiphyses after birth

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  1. endochondral


growth and remodeling- cartilage is replaced with bone, and the growth plate remains until adolesence then closes