Genes and Health (biological molecules) Exam Qs

Where is RNA polymerase found?

nucleus

Describe the role of tRNA in the production of a protein (2)

Explain how a change of one amino acid could lead to a change in the structure and properties of the haemoglobin protein (4)

Leptin is a protein hormone with a role in the control of appetite in humans. The leptin gene is located on chromosome 17

Describe how the primary structure of leptin enables it to be soluble in water (3)

Mutations to DNA can affect the structure of proteins produced in the cell.

Removing one base from a DNA sequence will affect the primary structure of a protein.

Changing one base for another may not affect the primary structure of a protein.

Explain why these two types of mutation have different effects on protein structure (4)

Describe how nucleotides join together to form DNA (2)

Explain why this mutation affects the function of the haemoglobin molecule (3)