Five Mechanisms of Antimicrobial Killing

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7 Terms

1
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what are the 5 mechanisms of antimicrobial killing

  1. cell wall

  2. plasma membrane

  3. nucleic acids

  4. protein synthesis

  5. metabolism


2
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antimicrobial killings

When a substance kills microbes by damaging them

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cell wall

Drugs inhibit cell wall synthesis and repair

4
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plasma membrane

drug damage the membrane and phospholipids causing important substances to leak out of the cell causing the cell to die

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nucleic acids

drugs prevent bacteria from copying DNA or making RNA stopping transcription and other essential cell processes

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protein synthesis

drugs stop bacteria from making proteins needed for growth and survival by targeting bacterial ribosomes interfering with translation

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metabolism

Drugs interfere with folic acid synthesis and other necessary metabolic pathways, preventing bacteria from making materials needed for growth