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What is the largest organ of the body?
The skin
What is skin vital for?
Temperature regulation, protection against water loss, and invasion from microorganisms
What are the two major regions of the integument?
The epidermis and dermis
Most of the epidermis is made of…?
Keratinocytes
Keratinocytes
Cells that produce the protective protein keratin
What is the most superficial layer?
The epidermis
What does the dermis primarily consist of?
Collagenous fibers
What is not a layer of the integument but anchors the integument to underlying bone or muscle?
The hypodermis
How can you determine the epidermis layer?
By the epithelial cells
How can you distinguish the hypodermis?
By the abundant adipose tissue
What are the keratinocytes of the epidermis composed of?
Keratinized stratified squamous epithelium
What is keratins purpose?
It protects the lower layers of the epidermis from wear and tear
Strata
The number of layers of the epidermis
Does the epidermis have blood vessels between the cells?
No
The epidermis is…
Nourished by the vessels in the dermis
What is the deepest layer of the epidermis?
The stratum basale
Basement membrane
The way the single layer of cells are attached to the dermis
Melanocytes
The specialized cells in the stratum basale
Melanin
Brown pigment produced by melanocytes
Melanin purpose
Protects the stratum basale from the damaging effects of ultraviolet radiation
The layer of numerous cells superficial to the stratum basale is?
The stratum spinosum
What are the stratum basale and stratum spinosum classified as?
The stratum germinativum
What layer of granular cells is superior to the stratum spinosum?
The stratum granulosum
What layer is superficial to the stratum granulosum?
The stratum lucidum
Where is the stratum lucidum located?
The palms of the hand and soles of the feet
What is the most superficial layer of the integument?
The stratum corneum
What is the epidermis made of?
Keratinized stratified squamous epithelium
What is the first phase that occurs in the stratum basale?
The cells are involved in rapid cell division
What is the second phase that occurs in the stratum spinosum?
Cells undergo a process of producing precursor molecules that leads to the general waterproofing of the cells by keratinization
What is the final phase that occurs?
Completion of the waterproofing process
How often does the epidermis renew itself?
Every 5-6 weeks
What is the dermis responsible for?
The structural integrity of the integumentary system
What are the two major regions of the dermis?
The papillary and reticular layer
What is the largest layer of the dermis?
The reticular layer
What are the majority fibers of the dermis?
Irregularly arranged collagenous along with lesser numbers of elastic and reticular fibers
What do collagenous fibers do?
Provide strength and flexibility
What do elastic fibers do?
Provide elasticity to the skin
Where do blood vessels occur?
In the dermis
What do the blood vessels do?
Bring nutrients to the dermis and epidermis
Why are dermal blood vessels important?
They release heat to the external environment
What do nerves in the dermis do?
Receive sensory inputs and transmit impulses to the central nervous system
What is sensory information received by?
Light touch receptors of the dermis
Where are tactile (meissner) corpuscles located?
In the upper portion of the dermis
Where are tactile (merkel) discs located?
In the upper and lower dermis
What do the two receptors do?
Allow for the perception of very slight touch stimuli
Where are deep touch or pressure receptors found?
In the dermis
What do lamellar (pacinian) corpuscles do?
Sense pressure
What are naked nerve endings in the dermis that respond to numerous environmental stimuli?
Pain receptors
What is another name for the hypodermis?
Subcutaneous tissue
How does the hypodermis attach to the dermis?
By collagenous and elastic fibers
What are two broadly distributed glands?
Sweat glands and sebaceous (oil) glands
What are the secretory parts of sweat glands composed of?
Simple cuboidal epithelium and connective tissue
What are the two different types of sweat glands?
Eccrine and apocrine
Eccrine glands
Sensitive to temperature and produce normal body perspiration
Perspiration reduces the temperature of the body by?
Evaporative cooling
Apocrine sweat glands
Secrete water and a higher concentration of organic acids than eccrine glands
What are two more localized glands?
Mammary and ceruminous glands
What do sebaceous glands secrete?
An oily material called sebum
What does sebum do?
Lubricates the hair and decreases the wetting action of water on the skin
Hair consists of keratinized cells produced in what?
Hair follicles
Shaft
The portion that erupts from the skin surface
Root
A deeper portion that is enclosed by the follicle
Hair bulb
The actively growing portion of the hair
What hair has a short growth phase and long rest phase?
Axilla, groin, eyelashes and eyebrows
What hair has a longer growth phase?
Scalp hair and beard hair
Dermal papilla
A region with blood vessels and nerves that reach the hair bulb
Root sheath
Formed by the outer dermal layer of connective tissue and an inner epithelial layer
Hair “standing on end” is caused by what?
The contraction of arrector muscles
Arrector muscle
A cluster or parallel smooth muscle fibers that connect the hair follicle to the upper regions of the dermis
What are arrector muscles controlled by?
The autonomic nervous system
Medulla
The central portion of the hair enclosed by an outer cortex
What is the layer superficial to the cortex?
The cuticle of the hair
What does most of the nail consist of?
The nail body
What part of the nail do you clip?
The free edge
Eponychium
The cuticle of the nail
Nail root
The area that generates the rest of the nail body
The nail bed is?
The layer deep to the nail body
Lunule
The small white crescent that occurs at the base of the nail
Hyponychium
The region under the free edge of the nail
On each side of the nail is?
The nail groove
Nail groove
A depression between the nail body and the skin of the fingers
Nail fold
The ridge above the groove