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the purpose of cell division
repair (replace damaged and existing cells)
growth (allow for growth and differentiation of cells)
reproduction (the production of new organisms)
the cell cycle
events that take place from one cell division to another
interphase
the stage between divisions where chromosomes aren't visible, cells spend most of there time there and do its assigned job
G1 phase
the cell produces new proteins, organelles duplicate,
S phase
DNA replication occurs so that each chromosome is made up of two chromosomes
G2 phase
the cells grow again and prepares for cell division
M phase
mitosis
prophase
chromosomes thicken and shorten to prepare for division, become visible, nuclear membrane disintegrates
metaphase
chromosomes meet in the middle, become attached to spindle fibres
anaphase
chromosomes are pulled apart by spindle fibres to opposite sides of the cell
telophase
chromosomes uncoil
spindle fibres disintegrate
nuclear membrane forms around the two nuclei
cytokinesis
cytokinesis in plant cells
cytokinesis in animal cells
a ring of actin fibres forms at the metaphase plate, the ring contracts forming a cleavage furrow that divides the cell into two
apoptosis
programmed cell death
purpose of apoptosis
is essential for development, shaping organs and tissues and removing cells that are old or infected
cells with DNA damage can pose as a threat, if they do to the rest of the organism, it is removed
will try to repair itself, if unsuccessful it is sent to apoptosis
the difference between the 2 ways of apoptosis
trigger is either external (DR) or internal (M), starts at the cell membrane (DR) of mitochondria (M)
the general process of apoptosis
1) cells with damage receive a signal to apoptosis (either pathway)
2) caspases are activated to break down the cell, cytochrome c from the mitochondria is released which activates more caspases, the membrane begins to bleb
3) the cell shrinks and the membrane continues blebbing due to caspases breaking down cellular components
4) the membrane continues blebbing
5) apoptotic bodies form
phagocytosis (apoptosis)
a macrophage that engulfs apoptotic bodies, not actually a part of apoptosis
binary fission
cell division in prokaryotic cells
difference between mitosis and binary fission
less complex in prokaryotic cells compared to eukaryotic
allows bacteria to replicate much faster
bacteria are the fastest reproducing organisms
the process of binary fission
1) the cell replicates its DNA
2) the cytoplasmic membrane elongates, separating the DNA molecules
3) cross wall forms, the membrane invaginates
4) cross walls form completely
5) two daughter cells are created
common features for all cells
plasma membrane, cytoplasm, nucleic acids, ribosomes
prokaryote cells
unicellular, lack membrane bound organelles,
specialized structures of prokaryote cells
flagella: tail life extensions, allow for movement
pili: allow for genetic transfer
fimbriae: important for attachment to surfaces
eukaryotic cell
unicellular (yeast) or multicellular (plant or animal cells), has lots of membrane bound organelles
structures unique to plant cells
cell wall, chloroplasts, plant vacuoles, and plastids
structures unique to animal cells
centrioles, lysosome
common features for plant and animal cells
plasma membrane, nucleus, endoplasmic reticulum, ribosomes, golgi bodies, mitochondria, vesicles, centrosome, cytoskeleton
mitochondria
powerhouse of the cell, makes energy, site of cell respiration (produces ATP),
chloroplasts
takes energy from the sun to convert it into glucose, the site of photosynthesis, consists or stroma (fluid) and grana, commonly found in the cells of leaves
the cell theory
all living things consist of at least one cell
all cells arise from pre-existing cells
cells are the smallest structural unit of life
SA:V
an important factor in the limitations of cell size and the need for organelles:
smaller cells have a larger SA:V making it easier to exchange nutrients
larger cells are less efficient
the fluid mosaic model
a way to describe the composition and structure of the plasma membrane
fluid in terms of the fluid mosaic model
the molecules within the plasma membrane are able to move, important for transport across the membrane
mosaic in terms of the fluid mosaic model
the membrane is composed of many different molecules
the function of the plasma membrane
to control what goes in and out of the cell, separates the extracellular environment from intracellular, allows cells to recognise each other, membranes also exist outside of the cell to establish components
phospholipid
naturally arrange themselves in a bi-layer due to the chemical properties of the head and tail, has a hydrophillic head and a hydrophobic tail
cholesterol
regulates fluidity of the membrane and reduces permeability, embedded in membrane, regulates temp in hot (prevents phospholipids from packing too tightly), and cold (prevents them from spreading apart)
proteins in the plasma membrane
peripheral = loosely attaches, important for cellular communication
integral = embedded in the membrane, important for transport
carbohydrates
important for cellular communication and maintaining membrane structure
glycoproteins = carbohydrate chain attached to a protein
glycolipids = carbohydrate chain attached to lipid
passive transport
no energy required, molecules move along their concentration gradient from high to low, there are different types depending on size and chemical properties
simple diffusion
the passive movement of a substance across a differentially permeable membrane along the concentration gradient, this is affected by:
permeability of the membrane, surface area, concentration gradient, and the distance of diffusion
osmosis
the passive net movement of water molecules through a differentially permeable membrane from an area of low solute to high solute - the pressure that makes water move is osmotic pressure
hypotonic solution (osmosis)
more solute inside the cell, the water moves into the cell and the cell enlarges
isotonic solution (osmosis)
equal concentration of solute inside and outside of the cell, no net movement
hypertonic solution (osmosis)
less solute inside the cell, water moves out of the cell and the cell shrinks
facilitated diffusion
the passive net movement of a substance through a protein channel (doesn't change shape, smaller substances) or a carrier protein (the molecule causes the protein to change shape, allowing the molecule to leave the other side)
active transport
energy requires, molecules move against their concentration gradient (in a way there not usually meant to go in) from low to high concentration
protein pump (active transport)
the active transport of a substance against the concentration via a protein pump, the pump changes shape (due to ATP) to allow molecules to pass through
endocytosis (bulk transport)
enables the transport of macromolecules (large molecules) into the cell, there are three main types:
phagocytosis (cell eating) = for large solid molecules such as food particles or bacterial cell
pinocytosis (cell drinking) = for liquids
receptor mediated endocytosis = a form of pinocytosis triggered by cell receptors on the plasma membrane
exocytosis (bulk transport)
the exit of large molecules from the cell
the vesicle carrying molecules for the export moves to the perimeter of the cell
vesicle fuses with the plasma membrane
the contents of the vesicles are expelled into the intracellular space
secretory pathway
the pathway from producing proteins to them exiting the cell, involves golgi body and er
how does the structure of the mitochondria assist
has a double membrane, inner (cristae) that provides a large SA for the production of ATP
how does the structure of the chloroplast benefit
contain chlorophyll to capture sunlight for photosynthesis