Paget’s Disease

What is Paget's disease?

Excessive or haphazard bone deposit and reoprtion

What is the newly formed, hastily made bone called

Pagetic Bone; it has an abnormally high amount of spongy bone compared to compact bone

What does Pagets Disease result in

Spotty weakening of bones

What do the bone cells do in someone with Paget's disease

Late in the disease, osteoclast activity wanes. Osteoblasts continue to work and often form irregular bone thickenings or filling marrow cavity with pagetic bone

Where does Paget's disease impact the individual

it can occur anywhere, but it usually localized. The spine, pelvis, femur, and skull and more often involved

Who does Paget's disease impact

it rarely occurs before the age of 40, and tends to impact older people. 3% of North American Elderly have it.

What causes Paget's disease

Its cause is unknown, but a virus may trigger it.

What can help to prevent bone breakdown in someone with Paget's disease

Drug therapies, like bisphosphonates and calcitonin