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priority concept: renal/urinary system 3
elimination, fluid and electrolyte balance, acid base balance
renal system functions: 6
regulate fluid volume/composition, filters waste, regulate bp, acid base balance, produce erythropoietin, convert vit D to active form
what does renin do?
assist in bp regulation/blood flow
what does prostaglandin do?
helps regulate GFR/blood flow to kidneys
what does bradykinin do?
increase blood flow
what does erythropoietin do?
stimulate bone marrow for RBC production
what does vit D do?
promotes calcium absorption in GI tract
RAAS system funtion pathway:
renin released from renal artery, angiotensin i, converting enzyme, angiotensin ii triggers aldosterone release, aldosterone increases Na/H2O, retention with high blood pressure
changes with aging renal/urinary: 5
decreased GFR, nocturia, decreased bladder capacity, weak urinary sphincters/short urethras in women, tendency to retain urine
decreased thirst can cause the risk of what?
dehydration
low GFR can cause:
kidney failure
over time, kidneys ________
shrink
less muscle =
less creatinine
what is creatine?
natural component that supplies energy to muscles
what is creatinine?
waste product of creatine metabolism
creatinine is a marker for what?
kidney filtration efficiency
overtime, the kidneys have a harder time concentrating urine, causing:
urine frequency
overtime bladder muscles weaken, leading to: 2
urine retention, incomplete emptying
women’s shorter urethra causes a higher risk of:
UTI
nursing considerations with older adults with renal/urinary changes: 3
monitor hydration, watch nephrotoxic meds, fall precautions
nursing interventions for older adults with renal/urinary changes: 3
BSC nearby, reduce fluids 2-4hr before bed, time diuretics
what drugs can worsen urinary retention?
anticholinergics
how to use cautions when administering nephrotoxic drugs?
check kidney function labs, identify high risk drug classes, Evaluate necessity/alternatives
what to remember when giving nephrotoxic drugs? 3
Use the drug only when clinically essential, for the shortest duration possible, consider safer alternatives
recognizing cues: health hx questions 6
family hx, chronic health issues, chemical exposure, diet, prescriptions/otc, changes in urine appearance/pattern/ability to void
recognizing cues: past medical hx indicators 5
kidney stones, infection, tumor, diabetes, htn
recognizing cues: exposure risks 5
metals, chemicals, travel, sexual risk, contrast/dye
recognizing cues: diet 3
recent changes, fluid intake, high protein
what should happen to proteins in the kidneys?
glomerulus blocks larger molecules like proteins/albumin and keeps proteins in bloodstream
what does proteinuria mean physiologically? 3
damage to glomerulus permeability, tubule damage reduces reabsorption, excess proteins overwhelm kidneys reabsorption capacity
what can cognitive function indicate renally?
waste build up
renal skin assessment: 3
yellow, rashes/swelling, uremic frost
what are renal rashes caused by?
uremia/toxin buildup in blood causing itching/rash
abdomen palpation is contraindicated if what is present? 2
tumor, aneurysm
what does a distended bladder sound like when percussed?
dull
male creatinine levels:
0.6-1.2mg/dL
female creatinine levels:
0.5-1.1mg/dL
BUN levels:
10-20mg/dL
BUN to creatinine ratio:
6-25
blood osmolarity levels:
280-300 mosm/kg
_____ only rises when about 50% of kidney function is lost
creatinine
bun acronym for:
blood urea nitrogen
BUN breakdown order: liver converts…
liver converts nitrogen from protein to urea which travels through blood to kidneys and leaves by urine
what is BUN?
waste product from protein breakdown that kidneys filter
what does BUN test for?
how well kidneys are removing waste
high ____ does NOT always indicate kidney disease
BUN
high ______ indicates kidney disease
creatinine
how to calculate BUN/creatinine ratio:
BUN divided by creatinine
BUN/creatinine ratio: high levels indicate 4
dehydration, reduced blood flow to kidneys, gi bleed, high protein intake
how does dehydration cause BUN/creatinine ratio to change?
BUN rises faster than creatinine
BUN/creatinine ratio: low levels indicate
liver disease, low protein intake/malnutrition, overhydration, muscle injury/kidney impairment
high blood osmolarity can indicate:
dehydration
low blood osmolarity can indicate:
blood is diluted, too much fluid
how does the body regulate high blood osmolarity?
ADH is released, causing kidneys to retain water/concentrate urine
how does the body regulate low blood osmolarity?
ADH secretion drops, kidneys excrete diluted urine
low BUN indicates:
chronic liver disease
if the nurse notices pt’s BUN is elevated, what should they look at next?
creatinine
if a pt’s BUN and creatinine is elevated, the pt may be dealing with: 2
chronic kidney disease, AKI/med toxicity
if a pt with high BUN/creatinine and have CKD, what should the nurse look at?
GFR to stage disease
stage 1 kidney disease GFR rate:
90+ mL/min
stage 5 kidney disease GFR rate:
<15 mL/min
if a pt’s BUN high/creatinine low, the pt is most likely:
dehydrated
common causes of AKI: CAKEMAN acronym
cyclosporine, ACEI, keppra, erythromycin/gentamycin, metformin, amphotericin, NSAIDs
normal urine specific gravity levels:
1.005-1.030
urine specific gravity ___________ in older adults
decreases
what does urine specific gravity measure?
density of urine to water
pH range of urine:
4.6-8
possible causes of orange urine: 4
chemo meds, dehydration, liver/bile duct condition, laxatives
possible causes of green/blue urine: 3
UTI/pseudomonas, propofol/methylene blue, food dyes
possible causes of red/pink urine: 3
hematuria, beets/rhubarb/berries, menstruation
possible causes of purple urine: 4
CAUTI/purple urine bag syndrome, gram negative bacteria
possible causes of dark brown urine: 4
liver disease, old blood, muscle breakdown, severe dehydration
what can indicate DKA in urine? 2
ketones, glucose
nursing safety priority: report the presence of ______/______- in urine of patient undergoing a screening exam to PCP
glucose, proteins
rules of 24fr urine collection:
first void discard, process starts over if one sample is missed, place foley in bath basin of water for 24rs
normal male GFR:
107-139 mL/min
normal female GFR:
87-107 mL/min
what is bedside sonography?
bladder scan
if a female with a hysterectomy needs a bladder scan, what mode should it be placed on?
male
KUB xray meaning:
kidneys, ureters, bladder
what to check for with pt undergoing CTA: 2
NPO status, dye/contrast allergies
diabetic pt’s on metformin going for contrast/dye procedure are at risk for:
lactic acidosis
how long does metformin be held before/after procedure?
48hr
why is metformin held during contrast/dye procedure?
metformin is cleared by kidneys can contrast can cause AKI, causing metformin to accumulate and cause lactic acidosis
what to check before pt goes for procedure with dye/contrast:
kidney function
who else checks kidney function before giving dye/contrast?
radiology
how soon can AKF occur after administering contrast?
48 hrs
who is more at risk for contrast induced nephropathy? 6
older, dehydrated, CKD, DM, CHF, current hypotension
when should metformin be administered after contrast/dye procedure?
kidney function
for renal US, bladder has to be ____
full
cystoscopy/cystourethroscopy preop checklist: 4
gen/local anesthesia with sedation, NPO at midnight, bowel prep, lithotomy position
cystography/cystourethrography checklist:
gen/local anesthesia with sedation, foley to instill contrast, void during xrays
why is contrast instilled through foley catheter during cystography/cystourethrography?
less damage to kidneys
what labs to check before kidney biopsy:
PT, PTT, INR, platelets
how long should pt lay flat after kidney biopsy?
4hrs
postop PRIORITY: kidney biopsy
internal bleeding
normal platelet levels
150-400
what does MAP measure?
organ perfusion
how to calculate MAP:
sys + 2 x dia / 3
normal map:
>65