Sympathomedullary Pathway (SAM Pathway)

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Vocabulary flashcards reviewing the anatomical structures, pathways, and hormones involved in the SAM pathway stress response.

Last updated 7:36 PM on 10/1/26
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9 Terms

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Amygdala

A part of the limbic system that is activated when a person enters a stressful or dangerous situation, sending a distress signal to the hypothalamus.

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Hypothalamus

A brain structure that receives a distress signal from the amygdala and activates the sympathomedullary pathway (SAM pathway).

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Sympathomedullary pathway (SAM pathway)

The pathway running to the adrenal medulla and the sympathetic nervous system (SNS), activated by the hypothalamus in response to stress.

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Sympathetic nervous system (SNS)

The nervous system branch activated via the SAM pathway that stimulates the adrenal medulla.

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Adrenal medulla

A part of the adrenal gland that is stimulated by the SNS to secrete the hormones adrenaline and noradrenaline into the bloodstream.

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Adrenaline

A hormone secreted by the adrenal medulla into the bloodstream that causes physiological changes to prepare the body for fight or flight.

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Noradrenaline

A hormone secreted alongside adrenaline by the adrenal medulla into the bloodstream in response to a stressful situation.

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Fight or flight

The state of physiological readiness prepared by changes caused by adrenaline following exposure to a stressful or dangerous situation.

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<p>SAM Pathway Flowchart</p>

SAM Pathway Flowchart

The step-by-step physiological process initiated when a person enters a stressful situation, leading to fight or flight preparation.