pcb 3703 lec 18
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How many ventricles are located within the brain?
Four ventricles.
What are the lateral ventricles?
Large cavities located within the cerebrum.
What medial partition separates the two lateral ventricles?
The septum pellucidum.
How many lateral ventricles are present in the brain?
Two lateral ventricles.
What and where is the third ventricle?
A narrow space in the middle of the diencephalon.
How is the third ventricle connected to each lateral ventricle?
By an interventricular foramen.
What is the shape and location of the fourth ventricle?
A sickle-shaped space between the pons and cerebellum.
How is the fourth ventricle connected to the third ventricle?
By the cerebral aqueduct.
Where does the fourth ventricle open medially and laterally?
To the subarachnoid space.
What does the fourth ventricle merge with after it narrows?
The central canal of the spinal cord.
What is cerebrospinal fluid (CSF)?
A clear, colorless liquid surrounding the central nervous system.
Where does cerebrospinal fluid circulate?
In the ventricles and the subarachnoid space.
How does the buoyancy function of CSF affect the brain?
It reduces the brain's apparent weight by 95%.
What specific percentage does CSF reduce the brain's weight by?
95%.
How does CSF protect the brain?
By providing a liquid cushion.
How does CSF maintain environmental stability?
By transporting nutrients and wastes and protecting against fluctuations.
What are the primary functions of the blood-brain barrier?
Regulating substances entering interstitial fluid and preventing harmful substance exposure.
What harmful substances does the blood-brain barrier protect against?
Drugs, wastes, and abnormal solute concentrations.
Are there any drugs that can pass through the blood-brain barrier?
Yes, for example, alcohol.
What type of specialized structures compose the blood-brain barrier?
Specialized capillaries connected by many tight junctions.
How are endothelial cells of the blood-brain barrier connected?
By many tight junctions.
What kind of basement membrane do blood-brain barrier capillary walls have?
A thick basement membrane.
What wraps around the capillaries of the blood-brain barrier?
Perivascular feet of astrocytes.
Which glial cell type contributes perivascular feet to the blood-brain barrier?
Astrocytes.
Where is the blood-brain barrier reduced for functional reasons?
At the choroid plexus, hypothalamus, and pineal gland.
Why is the blood-brain barrier reduced at the choroid plexus?
To produce cerebrospinal fluid.
What structure produces cerebrospinal fluid where the BBB is reduced?
The choroid plexus.
Why is the blood-brain barrier reduced at the hypothalamus and pineal gland?
To secrete hormones.
What are the four major brain regions?
Cerebrum, diencephalon, brainstem, and cerebellum.
What is the origin of all complex intellectual functions in the brain?
The cerebrum.
What structure separates the two cerebral hemispheres?
The longitudinal fissure.
What is the largest white matter tract connecting the cerebral hemispheres?
The corpus callosum.
Do cerebral hemispheres interact with the same or opposite side of the body?
The opposite side (contralaterally).
Which cerebral hemisphere frequently controls speech?
The left cerebral hemisphere.
How many lobes are present in each cerebral hemisphere?
Five lobes.
Which four cerebral lobes are named after overlying cranial bones?
Frontal, parietal, temporal, and occipital lobes.
Which cerebral lobe is not visible at the surface?
The insular lobe (insula).
What is the posterior border of the frontal lobe?
The deep central sulcus.
Which gyrus within the frontal lobe controls voluntary movement?
The precentral gyrus.
Which sulcus separates the inferior frontal lobe from the temporal lobe?
The lateral sulcus.
What are some primary functions of the frontal lobe?
Motor control, concentration, decision making, planning, and personality.
Where is the primary motor cortex housed?
Within the precentral gyrus of the frontal lobe.
What is another name for the primary motor cortex?
The somatic motor area.
How do motor pathways project from the motor cortex?
Contralaterally within the brainstem or spinal cord.
What is a motor homunculus?
A map showing proportions of the body controlled by the motor cortex.
Why are hands large on the motor homunculus?
Large brain areas control their precise movements.
Where is the motor speech area (Broca area) typically located?
In the inferolateral portion of the left frontal lobe.
What is the function of the motor speech area?
It controls movements required for vocalization.
Where is the frontal eye field located?
On the superior surface of the middle frontal gyrus.
What is the function of the frontal eye field?
It regulates eye movements needed for reading and binocular vision.
Where is the premotor cortex located relative to the primary motor cortex?
Anterior to the primary motor cortex.
What is the primary function of the premotor cortex?
It coordinates learned, skilled motor activities.
What is another name for the premotor cortex?
The somatic motor association area.
Where is the parietal lobe located on the cerebrum?
The superoposterior part of the cerebrum.
What ridge lies just posterior to the central sulcus in the parietal lobe?
The postcentral gyrus.
What is the primary general function of the parietal lobe?
Serving general sensory functions.
Where is the temporal lobe located?
Internal to the temporal bone, inferior to the lateral sulcus.
What are the primary functions associated with the temporal lobe?
Hearing and smell.
Where is the occipital lobe located?
In the posterior part of the cerebrum.
What are the main functions of the occipital lobe?
Vision and visual memories.
Where is the insula located?
Deep to the lateral sulcus, covered by the temporal lobe.
What are the primary functions of the insula?
Memory and the sense of taste.
Where is the primary somatosensory cortex located?
In the postcentral gyrus of the parietal lobes.
What receptors send sensory information to the primary somatosensory cortex?
Proprioceptors, touch, pressure, pain, and temperature receptors.
What does a sensory homunculus illustrate?
The amount of sensory information collected from each body region.
Which body regions have large areas on the sensory homunculus?
Lips, fingers, and genital regions.
Where is the somatosensory association area located?
Immediately posterior to the postcentral gyrus in the parietal lobe.
What is the function of the somatosensory association area?
It integrates touch information to identify objects by feel.
Where is the primary visual cortex located?
Within the occipital lobe.
What is the function of the primary visual cortex?
It receives, processes, and stores visual information.
What surrounds the primary visual cortex?
The visual association area.
What is the function of the visual association area?
It integrates and interprets color and form for recognition.
Where is the primary auditory cortex located?
Within the temporal lobe.
What is the function of the primary auditory cortex?
It receives, processes, and stores auditory information.
Where is the auditory association area located?
Within the temporal lobe.
What is the function of the auditory association area?
It integrates and interprets sounds.
Where is the primary olfactory cortex located?
Within the temporal lobe.
What is the function of the primary olfactory cortex?
It receives, processes, and stores odor information.
Where is the primary gustatory cortex located?
Within the insula.
What is the function of the primary gustatory cortex?
It receives, processes, and stores taste information.
Where is the prefrontal cortex located?
Rostral to the premotor cortex in the frontal lobe.
What functions are associated with the prefrontal cortex?
Complex thought, judgment, personality, planning, and deciding.
What is the function of Wernicke area?
It is involved in language comprehension.
Where is the central white matter located in the cerebrum?
Deep to the gray cerebral cortex.
What composes the central white matter?
Myelinated axons grouped into tracts.
What do association tracts connect?
Regions of the cerebral cortex within the same hemisphere.
What are arcuate fibers?
Short association tracts connecting neighboring gyri.
What are longitudinal fasciculi?
Longer association tracts connecting gyri in different lobes.
What do commissural tracts connect?
Regions in different cerebral hemispheres.
Name three examples of commissural tracts.
Corpus callosum, anterior commissure, and posterior commissure.
What do projection tracts link?
The cerebral cortex to inferior brain regions and the spinal cord.
Give an example of a projection tract.
Corticospinal tracts.
What is the internal capsule?
A projection tract passing between the thalamus and cerebral nuclei.
What is a petalis in cerebral lateralization?
The protrusion of a cerebral lobe on one side.
Which hemisphere is typically the categorical hemisphere?
The left hemisphere.
What functions dominate the categorical hemisphere?
Language abilities, categorization, and analysis.
Which hemisphere is typically the representational hemisphere?
The right hemisphere.
What functions dominate the representational hemisphere?
Visuospatial relationships, imagination, and sensory comparison.
What are cerebral nuclei?
Masses of gray matter located deep within the cerebrum.
What are the main functions of cerebral nuclei?
Regulating motor output, mood, emotions, and consciousness.