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Anatomy
studies structure of body parts and how they relate to one another
Gross Anatomy
study of large structures
surface anatomy
studies structures as they relate to the surface
cytology
study of cells
histology
study of tissues
embryology
studies developmental changes that occur before birth
chemical level
atoms form to combine molecules
tissues
groups of similar cells that have a common function
cellular level
cells are made up of molecules
organ level
organs are made up of different types of tissues
homeostasis
point of dynamic (changing) equilibrium; body's ability to maintain a relatively stable internal environment despite ever changing conditions
set point
level/range of "normal" for whatever variable is being considered
ex: blood glucose levels
receptor
sensor that monitors environment and responds to changes by sending information to the control center
control center
determines set point; analyzes input and determines appropriate response
effector
provides means for control center's response to the stimulus
What is the correct order of the components of the loops for homeostasis?
stimulus, receptor, afferent pathway, control center, efferent pathway, effector, response
Negative feedback
once stimulus occurs, and the control center and effector return the body to the normal position, stimuli stop as to not over-fix the problem
ex: blood glucose-once glucose levels return to normal, the stimulus for either raising blood glucose or lowering it ends
Negative feedback is the most common occurrance of homeostatic balancing
Positive feedback
happens in infrequent events that don't need continual adjustment
ex: giving birth-oxytocin is released which causes contractions to intensify, causing more oxytocin to be released, causing baby to eventually be expelled. Once baby is born, the stimulus for oxytocin to be released is shut off
neural (nervous system control)
quick, short lived, electrical signals
ex: allows you to get out of the way of danger quickly
hormonal (endocrine control)
chemicals sent out in blood stream; slower process that takes multiple steps; effects are more widespread and longer lasting because as long as the hormones are in the bloodstream, they affect the body
ex: growth, reproductive capability
axial
makes up main axis of body, includes head, neck, and trunk
appendicular
consists of appendages/limbs of body
superior (cranial)
toward the head/upper end of body
ex: the head is superior to the body
inferior (caudal)
away from the head/towards the lower part of the body
ex: naval is inferior to the chin
anterior (ventral)
toward or at front of body
ex: the breastbone is anterior to the spine
posterior (dorsal)
toward back of body/behind
ex: heart is posterior to the breastbone
medial
toward middle of body/inner side
ex: heart is medial to the arm
lateral
away from middle of body
ex: arms are lateral to chest
intermediate
between medial and lateral structure
ex: collarbone is intermediate between the breastbone and shoulder
proximal
closer to origin of body part or point of attachment of limb to trunk
ex: elbow is proximal to wrist
distal
farther from origin of body part/attachment of limb to trunk
ex: knee is distal to the thigh
superficial (external)
toward/at body surface
ex: skin is superficial to the skeletal muscles
deep (internal)
away from body surface/more internal
ex: lungs are deep to the skin
What are the trace elements in the body?
Copper and Fluorine
Sagittal plane
vertical plane that divides body into left and right
frontal plane
vertical; divides body posterior/anterior (front and back)
transverse/horizontal plane
horizontal; divides body into top and bottom
atoms
have protons and neutrons in nucleus; electrons in outer cloud
Are atoms electrically negative, positive, or neutral structures?
neutral
What determines if an atom is stable?
if the outermost shell is full of electrons (either 0, 2, 8)
Ions
atoms who have lost/gained electrons
How does an atom become an ion?
Ex: Na has 11 electrons/protons. This is an uneven number of electrons to have in its rings outside, so it needs to get rid of one to be stable
An ion is any atom that gets rid of or gains electrons in order to be stable
What are the major elements?
H, C, N, O
What are the lesser elements?
Na, K, Mg, Fe, Cl, P, S, I, Ca
What does major element mean?
They are the elements most commonly found in the body
cations
carry positive charge
ex: Na+
Sodium has 11 p and 11 electrons; it needs to lose 1 electron or gain 7 protons to be stable, but it is easier to lose 1 electron than gain 7 protons. So it is now extra positive=Na
anions
carry negative charge
ex: Cl-
Cl has 17 protons and 17 electrons; it is easier to add an electron than to give one away=Cl-
polyatomic ions
may be cations or ions; charged ion composed of two or more ions covalently bonded
ex: OH-, HCO3-
free radicals
destructive substances because they have an unpaired electron; you have to keep levels of free radicals; they disrupt proteins, nucleic acids, lipids in order to find a mate for their electron
isotope
structural variation of an atom; have the same number of protons and electrons, but different number of neutrons
ex: Carbon has several isotopes, 12C, 13C, 14C
what removes free radicals?
peroxisomes; Vitamins C and E decrease
compound
when two or more different kinds of atoms bind
ex: NaCl
What types of bonds can compounds have?
ionic and covalent
Ionic bond
electrons are lost or gained
ex: NaCl
Covalent bond
electrons are shared
Polar
electrons pulled more toward one atom forming dipole (Nonsymmetrical molecules that contain electrically unbalanced atoms); polar things only attract to other polar things, they can't attract to non-polar things
Non-polar
Electrically balanced molecules
Solutions
homogenous mixture
Solute
what is being dissolved
solvent
what you are dissolving into (in the body, water is almost always the solvent)
How do we express solution concentrations?
in percents and moles
percentages of solution concentrations
percent of solution that is solute
How much does a mole equal?
1 mole=6.02x10 to the 23 particles
1 mole of glucose = 1 mole of glucose over 1 liter of solution
moles tells you how many moles of solute are in a liter of solution
What is the difference between organic molecules and inorganic molecules?
Organic molecules contain carbon, inorganic don't
HOH
water; polar molecule; H2O can absorb heat or get rid of heat and still remain the same temperature
Negative pole
oxygen
positive pole
hydrogen
hydrogen bonding
intermolecular bonding in water; relatively positive hydrogen of one molecule attracted to relatively negative oxygen of another; reason for surface tension
What is the importance of water in the body?
it can get rid of heat or absorb heat and still remain the same temp; when water goes from liquid to gas, a lot of heat is liberated; lubricates joints, cushions, serous fluids
What percentage of the body is water?
92%
Acids
donate proton; gets rid of hydrogen ion
ex: hydrogen ion, H+
base
takes in hydrogen ion; releases hydroxide
ex: attract proton H+, release OH-
What is neutral on the pH scale?
7
what is considered acidic on the pH scale?
below 7
what is considered basic on the pH scale?
above 7 (alkaline)
Does a higher H+ concentration make for a lower pH or higher?
a higher H+ concentration makes for a lower pH and greater acidity
What is the optimal pH for blood?
7.35-7.45
How is pH calculated?
at a pH of 7, the number of hydrogen ions equals the number of hydroxyl ions; solutions with a pH below 7 have hydrogen ions that outnumber the hydroxyl ions; a solution with a pH of 6 has ten times the number of hydrogen ions as hydroxyl ions as a solution with pH of 7
What is a buffer?
minimizes pH changes in a solution by releasing ions (acting as acids) when pH begins to rise and by binding hydrogen ions (bases) when pH drops.
What determines wether a compound is organic or inorganic?
Organic has carbon backbone
What are 4 important classes or organic compounds?
carbs, lipids, proteins, nucleic acids
What are the different parts of carbohydrates?
Monosaccharides, disaccharides, polysaccharides
What are the different parts of lipids?
triglycerides, glycerol, fatty acids, phospholipids, steroids, eicosanoids
What are the different parts of protein?
amino acids, enzymes
What are the different parts of nucleotides/DNA?
nucleotides, ATP, nucleic acids
Monosaccharides
simplest form of carbs
Disaccharides
formed by two monosaccharides joined; nutritional source of monosaccharides
Polysaccharides
produce starch and glycogen
Triglycerides
body's most efficient form of stored energy
Glycerol
modified simple sugar used as solvent and sweetner
Fatty Acids
chains of carbon and hydrogen atoms with an organic acid group at one end
phospholipids
build cellular membranes
steroids
include hormones and cholesterol
amino acids
building block of protein
enzymes
speeds up chemical reaction
nucleotides
building block of nucleic acids
ATP
stores and releases chemical energy
nucleic acids
includes DNA and RNA