STROKE VOLUME changes that pathologically affect CO

negative inotropic changes: an effect that causes a decrease in the strength or force of the heart muscle's contraction

contractility changes that are pathologic would be ______

-Blockage to right or left coronary arteries suchas plaque results in decreased contractility

how does ischemia affect contractility

-Increased preload = increased blood volume, = fluid volume overload and increase in workload of heart

DECREASED=decreased BV = fluid vol deficit DECREASING CO & BP

how does preload affect CO

makes it difficult for ventricles to eject blood into receiving arteries

how does increased afterload affect stroke volume

lung disorders such as chronic bronchitis cause pulmonary artery vasoconstrinction, which INCREASES pulmonary vascular resistance

how does increased afterload affect the RIGHT VENTRICLE

atheroscelrosis of aorta & systemic arteries; peripheral arterial vasoconstrinction: HTN leads to increase of SYSTEMIC VASCULAR RESISTANCE

how does INCREASED afterload affect the left ventricle

-Anaphylaxis triggers overrelease of inflamm mediators

-Blood vessels overdilate

-Blood pools in periphery

-Decreases BP leading to shock and septic shock

potential chain of events of decreased afterload