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which sensory receptor cell is responsible for the detection of vibrations?
pacinian corpuscles
which sensory receptor cell is responsible for the detection of edges an isolate points (you can read braille)
Merkel's corpuscles
if the pacinian corpuscle has a weak stimulus, what would the intensity of the response be?
weak
what polarization are excitatory sensory receptors?
depolarizes
what polarization are inhibitory sensory receptor cells?
hyperpolarization
which pain nerve fiber is responsible for the first pain response?
delta fibers, SECOND is C fibers
difference between nociceptors (TRVP1 and TRPM3)
Mice lacking the gene for TRPV1 still respond to mechanosensory pain, but not to mild heat or capsaicin
Wernicke-korkasoff is a deficiency in what?
thiamine
what brain region is Huntington's disease caused by?
caused by progressive damage to the basal ganglia
at the neuromuscular junction, which transmitter is released?
Acetylcholine (ACh)
if you stub your toe and start to rub it, the rubbing will reduce the pain because of what?
the nociceptors will numb the pain
If a patient lost their hand, there would be a change in the brain. what is this called?
neuroplasticity
what are the two different types of non primary motor zones?
supplementary motor areas and the premotor cortex
what is the brain region responsible for helping you with find tune skilled movements?
cerebellum
skin receptors in the sensory pathway cross over to the contralateral side in which brain region?
the medulla
where does the motor system travel to?
frontal lobe (cerebral cortex), upper medulla, lower medulla, and to the spinal cord
main structures of the organ of corti
sensory (hair cells), framework of supporting cells, terminations of the auditory nerve fibers, and tectorial & basilar membranes
inner cells release what neurotransmitter?
glutamate
outer cells release what neurotransmitter?
Acetylcholine (ACh)
information from both ears/first binaural input is first integrated where?
the superior olivary
if someone gets severe noise damage, what specific ear structure will be damaged?
the hair cells in the cochlea
where do high frequencies have the greatest effect?
at the base of the cochlea (narrow and stuff)
where do low frequencies produce larger responses?
at the apex (wider and flexible)
difference between onset disparity and ongoing phase disparity
onset disparity is the latency difference between the two ears for the beginning of a sound. ongoing phase disparity is the difference between the ears for arrival of the peaks and troughs of the sound wave (latency whens sound arrives in the ear)
aphasia vs agnosia
aphasia is impairment is language while agnosia is a perceptual disorder (cannot recognize objects, people, sounds, or shapes)
different types of agnosia
associative: perceive objects, but cannot identify them
asterognosia: inability to recognize objects by touch
stimultanagnosia: can perceive the basic shape of an object but unable to perceive more than one object at a time
a patient has bilateral damage between the border of occipital lobe and temporal lobe. what symptoms will show?
symptoms of prosopagnosia and wernicke's are impaired ability to repeat words our phrases, cannot comprehend speech and cannot recognize familiar faces but can recognize by voice or clothing
what brain region is responsible for prosopangnosia?
fusiform gyrus
Broca's area vs. Wernicke's Area
difficulty in speech production vs. difficulty in language comprehension/meaningful speech
N400 error meaning
error in semantics (meaning)
ex: the man started the car engine and stepped on a pancake
N600 meaning
error in grammar
ex: the broker hoped to sell the stock was sent to jail
if the object was placed on the left hand, how would you identify it?
identify it using the left hand by drawing it or pointing
which taste receptor is for acids and uses protons?
sour (OTOP1)
if patient has damage to the olfactory cilia, what happens?
receptors cannot go to the glomerulus
how does the gustatory system signal?
from the tongue, to the brain stem nuclei, to the thalamus, to the somatosensory cortex
what is so unique about the olfactory system compared to other sensory systems
projected ipsilaterally (same side of body) and project to cortex without passing through the thalamus
humans have 400 types of factory proteins, but we can distinguish 1 trillion odors. why is that?
receptors have distinct but overlapping spatial distributions/vast combinations
taste papillae vs taste buds vs taste receptor buds
bumps on tongues that increase taste intensity vs structures inside the papillae that detect chemicals vs cells in the taste buds that detect flavors
what are spectrally opponent cells and whats their function?
have opposite firing responses to different regions of the spectrum. +L/M cell is stimulated above 600 nm and inhibited at shorter wavelengths. they send their outputs into many higher circuits—for detection of form, depth, and movement, as well as hue.
What is the function of V2 in the visual cortex area
neurons respond to illusory boundaries and complicit relations among the parts of their receptive fields. helps brain fill in gaps in visual scenes
rod photoreceptors
hyper polarizes when light comes in
photopic vs scotopic vision
photopic is color vision and scotopic is rod vision (dark)
dorsal vs ventral pathway
dorsal is spatial location of object while ventral is responsible for identifying objects