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Imipramine
TCA- improves mood and reduces depression
adverse: dry mouth, drowsiness, orthostatic hypotension
indications- depression, bedwetting, chronic pain
considerations: cardiac effects, suicidal ideations
Phenelzine (nardil)
MAOI- antidepressant improves mood and reduces
adverse effects: ortho hypo, weight gain, insomnia
indications: depression/ atypical depression
considerations: HTN crisis, no cheese, meat, fermented food, low tyramine diet
Prazosin (minipress)
alpha-1 adrenergic blocker
adverse effects: orthostatic hypotension, dizziness, headache
indications: HTN, BPH, PTSD-nightmares
Citalopram (celexa)
SSRI
adverse effects: nausea, sexual dysfunction, insomnia
indications: MDD, off label anxiety and panic disorder
considerations: worsening of suicidal, prolonged QT interval, increase heart rhythm problems
Venlafaxine (effexor)
SNRI- antidepressant
adverse effects- nausea, increased bp, sexual dysfunction
indications- MDD, GAD, social anxiety, panic
considerations: monitor bp, do not stop abruptly, suicidal thoughts
Carbamazepine (tegretol)
anticonvulsant
adverse effects: dizziness, drowsiness, nausea
indications: epilepsy, bipolar, trigeminal neuralgia
considerations: monitor cbc, liver function, and sodium levels, cause bone marrow suppression, liver toxicity, and hyponatremia, Steven Johnson syndrom, watch for rash
Clomipramine (anafranil)
TCA
adverse: dry mouth, drowsiness, constipation
indication: OCD, off label depression and panic
considerations: suicidal thoughts, changes in mood, cardiac abnormalities, seizures and heart related effects, don’t stop suddenly
Lithium (lithobid)
mood stabilizer for mania and depression
adverse effects: hand tremors, increased thirst and urination, weight gain
indications: bipolar and MDD
considerations: monitor blood levels bc of narrow therapeutic range, kidney levels, consistent salt intake and fluid intake, dehydration can lead to toxicity
Clozapine (clozaril)
second gen antipsychotic med
adverse effects: sedations, weight gain, orthostatic hypotension
indications: treatment resistant to schizophrenia and reduces suicidal behavior in schizophrenia disorder
consideration: monitor neutrophil count, risk of infection, blood glucose, weight, and lipid levels, myocarditis, constipation
Risperidone (risperdal)
atypical second gen antipsychotic med
adverse effects: weight gain, extrapyramidal symptoms, hyperprolactinemia
indications: schizophrenia, bipolar 1 disorder, irritability with autism disorder
considerations: monitor for extrapyramidal symptoms, blood glucose, lipid levels, neuroleptic malignant syndrome→ high fever, severe muscle stiffness, confusion, and unstable bp
Olanzapine (zyprexa)
atypical second gen antipsychotic
adverse effects: weight gain, drowsiness, hyperglycemia
indications: schizophrenia, bipolar disorder, treatment resistant depression combined with fluoxetine
considerations: monitor weight, blood glucose, and lipid levels, metabolic side effects, neuroleptic malignant syndrome→ high fever, severe muscle stiffness, confusion, and unstable bp