blood bank - antigens
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21 Terms
24 antigens in group
most high frequency
lutheran
antithetical antibodies
a is cold; IgM
b is warm; IgG
lutheran
antibodies have a characteristic loose, mixed field reactivity in tube
lutheran
shows dosage and are often weak
kidd
null phenotype
RBC’s resist lysis in 2 M urea
kidd
antibody titer quickly declines in vivo
kidd
associated with suppression of erythropoiesis
kell
Js^a and Js^b
kell
immunogenicity second to D
Kell
located on glycophorin B (GPB)
Ss
antibodies are IgG and react at AHG
Ss
located further down glycoprotein less affected by enzymes
Ss
Show dosage
IgM
MN
antigens are destroyed by common proteolytic enzymes
MN
antigens found on glycophorin A (GPA)
MN
naturally occuring antibodies
Lewis
passively absorbed onto RBCs
lewis
Secretor (se) must be present for conversion of one allele
lewis
null phenotype
black population 68%
white population is rare
duffy
destroyed by routine BB enzymes
duffy
null RBCs resist infection by P. vivax
duffy